Experiences with

Bydureon

An investigation brain penetrant, pegylated analogue of the glucagon-like peptide-1 (GLP-1) receptor agonist exenatide (Byetta, Bydureon) known as NLY01 did not lead to improvement in Parkinson's disease symptoms compared with placebo.

The protocol of the ‘Exenatide-PD3’ study has been published - An ongoing multicentre, double blind, parallel group, placebo controlled, Phase 3 clinical trial is assessing once weekly Bydureon treatment in Parkinsons over 2yrs https://bmjopen.bmj.com/content/11/5/e047993

I know several posts have been made regarding the exanatide trials, but I just stumbled across this brief video on YouTube and thought it was interesting. This video was made in 2019 and contemplates starting the two year Phase III trial in October of 2019, but the video says it was "published on March

Back on Bydureon and on a low dose of Crestor, my cholesterol has improved dramatically and my A1C is 7.0 which is right where my POC wants it. Triglycerides are slightly elevated, and liver enzymes are better than 6 months ago, but still slightly elevated.

The only change during that time was the lack of Bydureon. Finally back on the Bydureon for the last 7 weeks, as well as on a low dose of Crestor. I am both curious and hopeful that this improves my liver.

" [3] "Exenatide, sold under the brand name Byetta and Bydureon among others, is a medication used to treat diabetes mellitus type 2. ... It is a less preferred treatment option after metformin and sulfonylureas." [4] Byetta might be a nice fit for men on Enzalutamide.

I feel better on the Bydureon and can feel the effect that it has on my body by the way it wears off during the week. The issue of course is the cost of these medications. $1000 each per month without insurance!! Insane.

https://youtu.be/i1Cu7XJdAsQ

(Bydureon is just a form of exenatide that you only have to take once a week, instead of daily.)

This is a promising drug. https://youtu.be/fXg_T47Iob4 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31585-4/fulltext

All these issues are being addressed by medication such as Rytary and Zoloft as well as Propranolol, Trazodone and to some extent with a new diabetic medication: Bydureon (exenatide) that is supposed to help Parkinson’s patients. My tremors are well controlled with Rytary and Mucuna.

The type 2 diabetes drug exenatide (Bydureon, Byetta, AstraZeneca) has potential disease-modifying effects in Parkinson's disease, results of a randomized, double-blind, placebo-controlled trial suggest.

Hello all, my uncle is both type 1 and 2 diabetic for over 40 yes, he had been on byrueon for 1 week land 3 days and the medication had stopped working and he seems to be getting worse, he needs to constantly increase his insulin dosage which used to be effective at a lower amount without the bydureon