Experiences with

Axitinib

A Canadian friend who had kidney cancer which metastasised to his lung told us of a drug called Axitinib. He had been given a prognosis of 4 months but got on a trial using this drug and 48 months later is still NED. Does anyone have any info on this?

Hi, Dad’s oncologist has stopped the Erlotinib as last scan in Jan showed tumour growth. Private Liquid biopsy result just back, mutation EGFR p.L747_T751de. No treatment offered by NHS, oncologist thinks will be more harmful to dad but how does he know for sure? I read some PubMed data that restarting

Doxazosin, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize

Hello again everyone. I have just started on Tagisso which my doctor said is unlikely to work because my tumour doesn't have the right genetic 'make up'. But I live in hope, what else is there. He also said that if it didn't work there was nothing left. Over the past 2 years I have had Afatinib, immunotherapy

Hi just an update Have stage 4 lung but seems to be stable last scan showed my hip has been nibbled so having to have 5 rounds of radiotherapy Got my last bit of welding tomorrow I don’t Know if anybody else has had diarrhoea but Iv been terrible even a biscuit ! Anyway I’m still taking afatinib and

I was diagnosed with stage 4 lung cancer in early 2020 and was given the targeted therapy Afatinib. This was initially most effective but gradually stopped working and so the cancer spread further in the lungs. I then had five consecutive radiotherapy sessions which reduced the size of the main tumour

Hi Iv been on 50mg afatinib now for 14 months though I struggle with the rash Iv got antibiotics if it gets too bad just wondering if if ever settles on it’s own

Hi there Can anybody recommend a makeup that is suitable for rash prone skin I am on afatinib 50mg and have a red face at the moment 🙈though I won’t wear anything while I have it but after it’s gone I would like to get some slap on.

Hi I’m on afatinib 50mg have been ok but Iv got a rash on my face nose is blocked and eyebrows all dried up I look like Iv be burned any ideas how to relieve would be appreciated

NSCLung cancer changing to small cell.

Hi I was diagnosed with stage 4 lung cancer in February and I am now taking afatinib and the tumour has shrunk thank goodness tho now after all this time my arms and stomach have broke out in the “rash” I was told to plaster myself in cetriban but was wondering does anybody have any tips

I personally have problems getting motivated. I am watching too much rubbish on the tele, eating too many crisps and ice cream. I am about to run out of goodies. Hopefully my next Sainsburys delivery will have some of the treats I ask for. :) I am very lucky that I have a tiny patio and some pots so

Hi ! I’m new to this . My husband was diagnosed with metastatic adenocarcinoma of lung cancer (T4N3M1A) last month. He is on Afatinib the last two weeks but he is suffering from all three blowup of the side affects in the first week , mouth sore/ ulcers , , diarrhoea, face n chest rashes. Has been in

Now I am without treatment and my doctors propose Axitinib or participate in a trial of Votrient, which is not yet approved for the use of patients who have done immunotherapy. Is anyone in one of these programs? Has anyone used Axitinib and Votrient and which of them has been more toxic?

My husband recently had results confirming the re-occurrence of his lung cancer. As a second line treatment he is being offered a target treatment. His oncologist is trying to get a new treatment funded for him called Dacomitinib. Is anyone using this new drug, and if so how is it going so far? We have

I’m just wondering if anyone can give some experienced advice. My mum has been taking Afatinib for her lung cancer on a 20mg dose. The tablet has been doing its job, however my mums eyes have been very sore, should already suffers with dry eyes. My question is how she should be handling rest periods

Hi All My 71yo mother in law was recently diagnosed with adenocarcinoma stage 4. She was fit with very little symptoms. She has been taking Afatinib for 10 days now and is really struggling with side effects. She has diahorrea several times a day, acne rash on upper body particularly bad on her scalp

The FDA has expanded the indication for afatinib (Gilotrif) to include the treatment of patients with metastatic non–small cell lung cancer (NSCLC) whose tumors have uncommon EGFR alterations in L861Q, G719X, and/or S768I. http://www.onclive.com/web-exclusives/fda-expands-afatinibs-approval-for-lung-cancer

Hi am stage IV adenocarcinoma diagnosed August 2014, been on afatinib 20 mg all this time. Fortunately still here but the last 6 months have seen not a change in tumour size as per scans. However last 6 months has seen fatigue, mixing up words, needing to walk with stick, balance issues. According to

Hi guys. I'm Adam, I was diagnosed last April at the age of 37 with Stage 4 Lung Cancer which had spread to my spine. It was caught on an X-ray of my throat completely unrelated to the cancer. As a lifetime non-smoker it was a complete shock (and still is). Turns out it was due to DNA mutation). Ive