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Androgen deprivation therapy (ADT)
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What is the next step
My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had
ADT
yet and my MO wants to just wait and watch. What do you think?
My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had
ADT
yet and my MO wants to just wait and watch. What do you think?
old64horn
in
Advanced Prostate Cancer
4 months ago
Pluvicto damaging salivary glands?
Now on
ADT
holiday since 1-1-24, psa unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still not right yet.
Now on
ADT
holiday since 1-1-24, psa unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still not right yet.
Kayakbob
in
Advanced Prostate Cancer
26 days ago
2 or 3 yrs ADT
Is 3 yrs
ADT
with the first 2 years including abiraterone better than 2 yrs
ADT
with abiraterone in terms of survival or metastasis free survival. I am 18 months into
ADT
with abiraterone.
Is 3 yrs
ADT
with the first 2 years including abiraterone better than 2 yrs
ADT
with abiraterone in terms of survival or metastasis free survival. I am 18 months into
ADT
with abiraterone.
snugrose
in
Advanced Prostate Cancer
3 months ago
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Delay date for Lupron injection
Secondly, I am contemplating going on
ADT
vacation at the 18 months mark. Is it advisable? Thank you for any advice.
Secondly, I am contemplating going on
ADT
vacation at the 18 months mark. Is it advisable? Thank you for any advice.
John347
in
Advanced Prostate Cancer
3 months ago
What they don't tell you about Androgen Deprivation Therapy (ADT, hormone therapy) unedited version
ADT
Educational Program Info: https://www.lifeonadt.com/
ADT
Educational Program Info: https://www.lifeonadt.com/
Darryl
Partner
in
Advanced Prostate Cancer
7 months ago
1st PSA Post SBRT + ADT: A Bounce?
Zelefsky) in early January of this year. 6 months of
ADT
(Orgovyx) ended May 23, 2023. At the end of
ADT
, my PSA was <0.05 and Testosterone was 4. My first PSA Test was last Wednesday at Penn Medicine in Philly (9 months post RT and 4.5 months post
ADT
): Testosterone back: 431.
Zelefsky) in early January of this year. 6 months of
ADT
(Orgovyx) ended May 23, 2023. At the end of
ADT
, my PSA was <0.05 and Testosterone was 4. My first PSA Test was last Wednesday at Penn Medicine in Philly (9 months post RT and 4.5 months post
ADT
): Testosterone back: 431.
Longrunner
in
Prostate Cancer Network
7 months ago
TRT Causing Breast Enlargement
Am considering it because two years after
ADT
. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Am considering it because two years after
ADT
. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Jack54
in
Advanced Prostate Cancer
5 months ago
First MO visit
ADT
treatment right away?
ADT
treatment right away?
RedBird713
in
Advanced Prostate Cancer
2 months ago
Relugolix/Orgovyx or Enzalutamide/Xtandi?
But, long story short, he has been on
ADT
vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched to Nubeqa).
But, long story short, he has been on
ADT
vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched to Nubeqa).
FaithOverFear104
in
Advanced Prostate Cancer
2 months ago
Can Nubeqa (Darolutamide) be used instead of normal ADT drugs for localized PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
Mike58
in
Advanced Prostate Cancer
6 months ago
Update On Eclipse Trial-another failure. Has LU-177 worked for anyone?
Due to cardiovascular problems, going back on
ADT
is a last resort. What do you guys think?
Due to cardiovascular problems, going back on
ADT
is a last resort. What do you guys think?
SViking
in
Advanced Prostate Cancer
4 months ago
Long term ADT bone loss mitigation tips?
My post RP BCR was diagnosed 8 months ago when they said, "you will be on
ADT
the rest of your life". I am on Lupron and abiraterone 4 months now. I am taking 1000mg of calcium per day and 2000IU of D3 per day. If I am lucky enough to last years, what else can I do to prevent the loss of bone?
My post RP BCR was diagnosed 8 months ago when they said, "you will be on
ADT
the rest of your life". I am on Lupron and abiraterone 4 months now. I am taking 1000mg of calcium per day and 2000IU of D3 per day. If I am lucky enough to last years, what else can I do to prevent the loss of bone?
jackwfrench
in
Prostate Cancer Network
4 months ago
Clinical Trial Considerations??
It has a pretty lengthy list of side effects in addition to the traditional
ADT
treatment. While I want to help the PC cause, the standard treatment plan has a very high likelihood of success even with high-risk G8. The trial uses SBRT and a shorter
ADT
regimen.
It has a pretty lengthy list of side effects in addition to the traditional
ADT
treatment. While I want to help the PC cause, the standard treatment plan has a very high likelihood of success even with high-risk G8. The trial uses SBRT and a shorter
ADT
regimen.
CubFan
in
Prostate Cancer Network
7 months ago
WORRIED ABOUT REOCCURRENCE???
Stopped IMRT 1 year ago and stopped
(4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
Stopped IMRT 1 year ago and stopped
(4 mos) 9 months ago...
9/23/23 Blood Test PSA .1 --- PSA FREE undetectable and Testosterone was 98
3/4/24 Blood Test PSA .2 ----Psa Free Undetectable and Testosterone not in yet.
JWS13
in
Advanced Prostate Cancer
2 months ago
Testosterone volatility
It was not measured again until after I started on
ADT
and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason 9.? How Volatile are "T" numbers?
It was not measured again until after I started on
ADT
and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason 9.? How Volatile are "T" numbers?
Scout4answers
in
Prostate Cancer Network
2 months ago
ADT response and questions for MO
As he's got low volume, was healthy, lean (prior to
ADT
) and fit, and min symptoms we are wondering if he can go hard for total remission. Seems like
ADT
plus RT will knock it back for a while, until it comes back as CRPC.
As he's got low volume, was healthy, lean (prior to
ADT
) and fit, and min symptoms we are wondering if he can go hard for total remission. Seems like
ADT
plus RT will knock it back for a while, until it comes back as CRPC.
Lovecherries
in
Advanced Prostate Cancer
2 months ago
PSA slightly rose after 8 months undetectable
I am 57 and on
ADT
(Firmagon+Zytiga+Prednisone) after surgery in 2022 and 39 sessions of RT in 2023 (Jan Feb). Till now I has been undetectable but at November my bloodwork showed PSA risen to 0.04. Should I be concerned or could it be just random fluctuation? Thanks for your reactions.
I am 57 and on
ADT
(Firmagon+Zytiga+Prednisone) after surgery in 2022 and 39 sessions of RT in 2023 (Jan Feb). Till now I has been undetectable but at November my bloodwork showed PSA risen to 0.04. Should I be concerned or could it be just random fluctuation? Thanks for your reactions.
noasim
in
Advanced Prostate Cancer
5 months ago
PSA doubled in last 30 days after 4 months stable since Provenge. What's next?
I have been off of all
ADT
since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA had been climbing quick until leveling off at 1.77 even as testosterone slowly returned.
I have been off of all
ADT
since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA had been climbing quick until leveling off at 1.77 even as testosterone slowly returned.
SViking
in
Advanced Prostate Cancer
2 months ago
Pain post SBRT
Started on
ADT
(Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted for 3-4 hours.
Started on
ADT
(Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted for 3-4 hours.
Eggdoc
in
Advanced Prostate Cancer
20 days ago
Testosterone Recovery Time after 1 Year of ADT?
I am ending
ADT
at 1 year. As of today my Testosterone is <0.01. It was 4.3 mg/mL before my first shot. Is there any data on how long it will take a 61 YO to start to see some T come back? Anyone here of a similar age and duration have any words or wisdom on what to expect?
I am ending
ADT
at 1 year. As of today my Testosterone is <0.01. It was 4.3 mg/mL before my first shot. Is there any data on how long it will take a 61 YO to start to see some T come back? Anyone here of a similar age and duration have any words or wisdom on what to expect?
OldVTGuy
in
Prostate Cancer Network
3 months ago
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