Vaping-induced Sweet's syndrome

[Shell567]

Vaping—not such a sweet alternative: a case report of bilateral hand Sweet syndrome, 2024.

First reported case of neutrophilic dermatosis of the dorsal hands, a Sweet's syndrome variant, triggered by vaping.

"A 64-year-old, right-hand-dominant, retired female presented to our hospital with bilateral hand ulcerated lesions. She reported that the lesions started as red patches on her right hand that increased in size, blistered and changed colour to purple, and eventually progressed to her left hand. She reported quitting smoking tobacco and starting vaping nicotine three weeks prior. She initially held the vape using her dominant right hand between her thumb and index finger, but after developing blisters she switched to her left hand, which also developed largely symmetrical lesions. She reported that the vape got hot during use but not hot enough to cause thermal burns."

"None of the previous studies reported vaping-induced SS. Vaping contains between 60 and 120 compounds on average in variable concentrations. Many of those compounds are toxic substances such as heavy metals, volatile organic compounds, propylene glycol and harmful solvent by-products (eg, formaldehyde), that can promote inflammation and allergic reaction. Moreover, Lalla and colleagues noted that the higher the concentration of propylene glycol as a solvent, the more intense the reaction in both allergic and irritant contact dermatitis." ajops.com/article/94716

[Shell567 Administrator Sweet's Syndrome UK]

Neutrophilic dermatosis of the hands dermnetnz.org/topics/neutro...