Hi Has anyone taken Kasquali
Did you have any side effect?
Kasquali : Hi Has anyone taken... - SHARE Metastatic ...
Kasquali
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nancypont
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Hi Nancy. Yes, I was on Kisqali for about 18 months with no side effects. Before that I was on Ibrance, again no side effects apart from one bad mouth ulcer in the first month.
Good luck with your treatment.
Hi Nancy,
I've taken Kisqali for 3 years. I was started on 600 mg in 2022, and it took about 10 months to reduce my cancer antigens (CAs) to a normal level. I now monitor my CAs myself, and I've reduced my amount of Kisqali to 400 mg on weekdays only.
Since I'm 79 years old, my lack of energy may be attributed to age as much as medication. However, I still maintain a large house on my own since my husband died in 2023.
Best of wishes, Cindy
I am so sorry for the loss of your husband. I know that it's difficult going through cancer without our significant other. Hugs 🤗🤗. Alicia
Thank you for your sympathy, and hugs, Alicia! It has now been 21 months but I still miss David's company daily. Is your knowledge based on personal experience? If so, I'm sorry!
Hugs, Cindy
Yes I lost my husband 5 years ago to cardiac arrest. It was very traumatic for me and the grief for years unbearable. I'm doing much better now but I dearly miss him. I had to come to an acceptance in my heart that he's gone, I finally found some peace.
God bless you. I’m so sorry for your loss. I am glad you are gaining some acceptance and peace. My stage IV bRCA is widespread. I was first diagnosed with Stage one in 2000. Then stave IV in 2015. It is widespread in my lungs, spine, right hip and now peritoneal cavity. 25 years I have lived since that initial diagnosis and I know I haven’t much time left. My sweet husband (34 years) will be devastated. My children and grandchildren will be crushed. For me, the worst thought of dying is knowing the impact it will have on those I love. Nothing can prepare you for such a loss. I’m on the other end of what you have had to deal with, I just hate what this is doing to my family. I am so glad you are working through the grief and hope you continue to do well.
Namaste’
Oh I am so sorry. I understand about leaving loved ones behind. Especially when your time is limited. I have two terminal cancers - stage 4 metastatic breast cancer and limited stage small cell lung cancer, so two different cancers in my lungs. The SCLC is aggressive and I am going through treatment for for both of them simultaneously. I just started immunotherapy (after chemo and radiation) for the small cell lung cancer and it'll buy me time. My adult children will have a hard time. So I have created grief comfort boxes for each of them and for my sister too which I am very close to, she will have the worst time without me. We talk for hours every night. So the tears flow every time I think about it. Hugs 🤗
Goodness, I’m so sorry for all you are experiencing! It is so devastating. I can’t dwell on it or it would be impossible to function . I try to take a day at a time and stay busy doing the things that make me happy. Please tell me more about the comfort boxes you mentioned! I lost my sister in 2023, she had a very aggressive neuroendocrin cancer of the esophagus and then also developed 2 other tumor types - all in the GI tract. I miss her so much!!! We found much comfort and understanding in each other.
Take care of yourself…..
Namaste’
I bought three different large boxes - like a masculine one for my son and two feminine looking ones for my daughter and sister and filled them with gifts like books on grief related to losing your mom and losing your sister, blankets for son, daughter and sister, jewelry items that say sisters, daughter, angel statues, photos, and I will be adding cards for birthdays, holidays, anniversaries etc. for each year up to 5 years, prayer cards and I have a book my daughter bought me called "tell me your story mom" that I am writing in - it's responses to questions. (She bought me that book on Mother's Day two years ago just before I was diagnosed with cancer). I bought a big box of all kinds of cards on Amazon for the birthday cards etc. I want them to know I won't ever forget them and I will love them forever.
Hi Cindy. I just wanted to acknowledge the loss of your husband. My husband of almost 39 years has been my rock along this MBC journey and due to your stated age I am assuming that you likely had been married a long time too. I hope you have other people around you if you do indeed need help at any point. Take care.
Thank you for your acknowledgement, Awesome! David and I only married in middle age, 28 years ago, so you two were much younger than we were. I do miss him daily, but I do remind myself that he chose to go.
He was diagnosed with a brain tumour after noticing a weakness in his left side when we were tourists in Spain. He declined to have treatment there, preferring to come home to Saskatchewan where no treatment was offered. He feared being incapacitated, and asked for MAID (medical assistance in dying) which is legal here.
Still hard for you. MAID is legal here too. Tough because if he developed the weakness again after he returned from Spain he would have been offered Tissue plasminogen activator (tPA) which is a thrombolytic treatment to help dissolve the clots that could have lead to a full blown stroke. The treatment window is 3 to 4.5 hours following the development of symptoms so that's why he wasn't offered it upon arrival back from Spain. Yes we were married younger as I am only 61 now. My husband is my rock and there for me every step of the way, although it is a difficult journey for him too. Take care and thanks for responding.
The weakness in his left side wasn't that dramatic. He was still able to walk up the airplane steps. Our tour guide hired a nurse to accompany him home first class (no cost to us). David was not in pain, but was very modest, and feared incapacitation. I'm glad your husband is made of sterner stuff.
Hello! I am on Kisqali and have been for about three month at 400mg. I don’t have any side effects other than fatigue but I think that is from cancer in general. Good luck!! Allison 
I was put on Kisqali in Fall of 2022. It was the highest dose and the side effects were so bad I only lasted one round. My ANC dropped to .4 after only a few weeks. I contracted Covid despite having had my Covid shot a few weeks before starting the Kisqali. I was bedridden and couldn’t function. My doctor wanted to keep me on the drug and lower the dose, but I declined and stopped it. I took fulvestrant alone for a couple of years before adding in Truqap in June, 2024.
Hi,Nancy !!I'm on Kisqali and anastrosole.I don't have any sideeffects.(except mild nausea in first weeks,but not now)
My onc.started my Kisqali with lower dosage first,which is 200 mg.
I'm now on 400 mg.
Best wishes from Sydney, Australia ☺️
Hello and happy new year!
Kisqali was my first treatment. It very effectively reduced my primary tumour and lowered my markers in the ,roughly, 2 months that I took it at the highest dose.
In my case it overloaded my liver function and I was switched to Ibrance after a medication free period to detox and get the liver enzymes back to normal levels.
Symptoms to look out for are body rashes similar to heat rash, tiredness and extreme brain fog.
That being said many people take it with no side effects at all...so please don't worry.
It seems to be the go to, first in line, of the 3 CDK 4/6 inhibitors....ibrance and Verzenio being the others....everyone reacts differently.
As you no doubt already know...drinking lots of water throughout the day helps to flush our systems and also reduced possible reactions....I drink about 2-3 litres of water and hot tea daily. I'd also be careful with any additional load to liver/ kidney function....any extra supplements or over the counter meds can tip the ballance....so I'd recommend only taking things prescribed by your oncologist.
Wishing you all the best
Zoe
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I took Kisqali for about 12 months. I had a lot of fatigue and developed pneumonitis from it. Even though the pulmonolgist said I am ok now I have not been able to dance. I have been on Orserdu for 9 months and seem to have no side effects.
