Combining pregabalin and gabapentin

[Believer1234]

Hi - has anyone had any experience in doing this? I'm currently doing 150mg PG and 600mg GP. The GP is refusing to prescribe both but I'm finding I have better results doing this.

Also has anyone had any recent experience with Botox? My physio came up with a very positive research paper on it and apparently it's currently prescribed for spasticity. I've seen some old post but nothing recently

Thank you!

[SueJohnson]

Why is your doctor refusing to do it? There is certainly no reason not to.

I haven't had any experience in it, but Botox injections at the applied dose can reduce the severity of symptoms in RLS up to 6 weeks. Moreover, the quality of life of the RLS patient can be improved for up to 6 weeks post-injection, and pain and discomfort diminished for 4 weeks." according to a placebo controlled study. Injections were into the tibialis anterior, gastrocnemius, and hamstring muscle each side. Perhaps this is the same study you saw.

[Believer1234 in reply to SueJohnson]

Thanks Sue - he couldn't really explain it apart from saying that the effect of combining could cause breathing difficulties and unconsciousness and then fell back on that he wasn't allowed to do it. I just wondered if anyone else had managed to get both prescribed which means that he was talking rubbish!

Yes on the subject of Botox, again I wondered if anyone else was using this, what the results were and how easy it was to get on prescription?

[SueJohnson in reply to Believer1234]

That's ridiculous. Since you have tried it, you can tell him it doesn't cause breathlessness for you and how well it works. And it certainly doesn't cause unconsciousness. That is not a side effect of either. They are basically the same drug. And who is telling him he can't do it? Can you get a referral to a neurologist who would certainly know better or can you change doctors?

And here is an article you can show him pubmed.ncbi.nlm.nih.gov/290...

[Believer1234 in reply to SueJohnson]

That's great - thanks Sue!

[LavendarCat in reply to Believer1234]

Hello! I have combined Gabapentin and Pregabalin. Works just fine!