Gabapentin for Sleep?: I was taking... - Restless Legs Syn...

Restless Legs Syndrome

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Gabapentin for Sleep?

zeusop profile image
14 Replies

I was taking Gabapentin originally to help with mild RLS symptoms which are even less evident with iron supplementation. As a sufferer of insomnia I have kept taking 200 mg Gabapentin together with 50 mg Trazodone before bed and have found that combination very effective. Is there a problem continuing that as a long term solution?

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zeusop
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SueJohnson profile image
SueJohnson

There shouldn't be. I'm glad you found something that helps your insomnia.

zeusop profile image
zeusop in reply to SueJohnson

Thank you Sue. Appreciate your prompt response.

You might find that half or even 1/4 of a 50mg tablet is even more sedating. Not sure what type of iron you take but I use ferrous bisglycinate an hour before bed. Not only does it get rid of my RLS in one hour but I find it mildly sedating.

zeusop profile image
zeusop in reply to

Interesting. I take 65mg Iron (325 mg Ferrous Sulfate) and usually in the morning with Vitamin C. Is that also mildly sedating? And the Trazodone in a lesser amount is actually more effective? That would be a good thing. As I wrote in my original query I also take 200 mg Gabapentin which I doubt does much for RLS at that dosage but seems to have helped my insomnia. I'm all for eliminating all drugs if at all possible. I wonder whether the smaller Trazodone dosage with Iron at night would allow me to drop the Gabapentin? Any thoughts on that. And thank you very much for your response.

in reply to zeusop

I’d be willing to bet $1,000 that if you took two iron tabs (preferably ferrous bisglycinate) an hour before bed on an empty stomach and 1/2 trazodone that you would sleep well without the Gabapentin. My “chelated” iron might be more sedating because it is formulated with Glycine which is a sedating substance.

If you find 1/2 trazodone works then try 1/4. I would take the trazodone about 15 minutes to 20 minutes before bed

Please let me know how it goes 💫

in reply to

I always wondered why the ferrous bisglycinate was so sedating to me. Plus, no one else on here reported same. Then someone suggested it might be the Glycine in it. So this is interesting: thesleepdoctor.com/sleep-ai...

It is not as sedating to me as it once was but still gets me to where I need to be…asleep without RLS

zeusop profile image
zeusop in reply to

Thanks so much for your response. I can certainly give it a try. I'll give you some feedback afterwards

SueJohnson profile image
SueJohnson in reply to zeusop

Did you have your ferritin checked? If so what was it?

zeusop profile image
zeusop in reply to SueJohnson

Hi Sue. Have a follow up appt with the Doctor November 1st. I will be checking my Ferritin level before. I'll tell you as soon as I know. Thanks

zeusop profile image
zeusop in reply to SueJohnson

Hi Sue. Got my results. My Ferritin level was 69

SueJohnson profile image
SueJohnson in reply to zeusop

OK - that is actually good because improving it to 100 or more helps 60% of people with RLS. You do need to take your iron at night, not in the morning as it is absorbed better then. Take it at least 1 hour before a meal or coffee and at least 2 hours after a meal or coffee since iron is absorbed better on an empty stomach. Don't take tumeric as it can interfere with the absorption of iron. If you take magnesium or calcium take them 2 hours apart as they interfere with its absorption. Also antacids interferes with its absorption. It takes several months for the iron tablets to slowly raise your ferritin. Ask for a new blood test after 3 months. Also see my reply to Hemi1980.

Hemi1980 profile image
Hemi1980

Theres no choices but long term onece you start them you cant quit them at all alot of serious side afect if you do even death i would stay away of gapapentine

zeusop profile image
zeusop in reply to Hemi1980

For 200 mgs? Death? Seriously?

SueJohnson profile image
SueJohnson in reply to Hemi1980

That's ridiculous. You do need to reduce them slowly to avoid withdrawal effects and if one does there will be none.

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