Pregabalin fatigue: For what it is... - Restless Legs Syn...

Restless Legs Syndrome

22,278 members16,301 posts

Pregabalin fatigue

wantokporo profile image
10 Replies

For what it is worth, my primary care doctor said the daytime sedation after years on 150 mg. of Pregabalin could, unfortunately, be the medicine. Thyroid tests came out normal.

Written by
wantokporo profile image
wantokporo
To view profiles and participate in discussions please or .
Read more about...
10 Replies
SueJohnson profile image
SueJohnson

Yes - that can be a side effect of pregabalin.

LotteM profile image
LotteM

Difficult to accept and deal with. I can relate. I have the samen on buprenorphine, even at a low dose. Acceptance and stay within limits. But it continues to feel unfair, as not all get it. It it is also not uncommon.

Yes, that's what my sleep specialist and general physician have suggested is the cause of my daytime fatigue (exacerbated when I take clonazepam).

I'm linking something I posted a while back

healthunlocked.com/rlsuk/po...

Nikos64 profile image
Nikos64

I was also on 150mg of pregabalin and also experienced severe fatigue. Not only that, it made waking up extremely difficult and I missed work on a few occasions. Since it was interfering with work I asked to be taken off it. Watch out for the weight gain too!

Medici profile image
Medici in reply toNikos64

Have you stopped it now and if so has the weight gain reduced please?

wantokporo profile image
wantokporo in reply toMedici

No I didn't stop it because -- on balance -- my life is better despite the sedation. I didn't have the weight gain side effect. I have tried SOOO many other things.

Medici profile image
Medici in reply towantokporo

Thank you. I know the feeling.

Nikos64 profile image
Nikos64 in reply toMedici

I stopped it. The sedation was unacceptable. The weight gain slowly went away after a few months. I did not think this medication was right for me.

Medici profile image
Medici in reply toNikos64

Thank you Nikos. How was your RLS when you stopped and what do you take now?

Nikos64 profile image
Nikos64 in reply toMedici

I was on 50mg of Tramadol and 150mg pregabalin. The doctor simply replaced the pregabalin with an extra 50mg of Tramadol. This worked quite well. Lately the RLS has gotten worse and the doctor added Horizant. RLS has been my tormentor since childhood. It got worse after I turned 50 which is when I sought professional help. Best wishes in finding an effective medication through your doctor!

Not what you're looking for?

You may also like...

Pregabalin

Hi I wondered if anyone has experienced Pregabalin. I am currently on 5mg of Ropinerol and finally...
WC13 profile image

Pregabalin

Hi, I recently changed medication from. Pramipexole which was augmenting to Pregabalin. I have...

Pregabalin

I have been on 600mg of Gaberpentin for at least two years for RLS and a couple of weeks ago I...
DisneS profile image

Pregabalin

Hello I’m looking for some positives on Pregabalin use. I’ve been through ropinirole and...
Pam34 profile image

Pregabalin

just started journey to come off Ropinirole after 18 years. Still currently taking 4 x 0.5 mg...
SilverEvie profile image

Moderation team

Kaarina profile image
KaarinaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.