A question

[Debsamuels]

No worries. I can think of a ton of things that RLS can stand for Not repeatable. On a serious note did anyone listen to radio 2 the other day. Let’s hope one day we can sort it. My own theory is this complex condition is related to other body systems. I am no scientist but just wondering if anyone also has IBS.

[Hidden]

Your new thread looks like a reply to someone and is missing something.

On the other part I was diagnosed with IBS but after many years of suffering I gave up ALL dairy and have no symptoms.

[Hidden in reply to Hidden]

I think it's a response to the "what's in a name" post.

[Hidden in reply to Hidden]

Yes I am sorry to report that the writer of "What's In a Name" and many other very humorous and poetic posts has left this forum due to unfair criticism.

The writer was a person of great integrity and kindness, but felt he had no option but to leave.

Sad, very sad, we must all consider our words in the future as this forum is (supposed) to be about supporting each other not belittling each other.

This is not aimed at you Manerva, as I know you often shared humorous banter with this RLS member.

[Gmc54 in reply to Hidden]

Do you mean Bear????? If so I used to really look forward to his posts, and will miss him.

[Hidden in reply to Gmc54]

Have sent pm 😞

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Sorry to confuse the issue, but what exactly do you understand by the term RLS ( meaning restless legs syndrome in this case)?

Some members seem quite dismissive of the idea that Primary (Idiopathic) RLS and Secondary RLS might be different beasts (they are both beasts) and both can be put in the same (conceptual) box.

Some members have posted of their experience of their RLS being related to their IBS, SIBO or the vagus nerve .

This suggests that there may be at least a "correlation" between these gastrointestinal problems (and visceral nerves) and RLS. This doesn't mean there's a "cause effect" relationship i,e, that they cause RLS. There may be as yet some undiscovered third factor which connecst the two.

E,g, there may be a correlation between Gastroesophageal reflux disease (GERD) and RLS. However, in this case the 3rd factor may be a proton pump inhibitor antacid, used for GERD, that causes B12 and iron malabsoprtion.

Overall, I confess to being ignorant about this, as there doesn't seem to be a great deal of research into it. Perhaps there should be.

The other thing about this is that accepting that IBS, etc does cause RLS is it secondary or primary?

There's a lot of research on primary RLS that doesn't really mention IBS etc.

I realise I'm probably legally wrong and outnumbered in feeling the idea that RLS and WED are synonymous is unhelpful, because you'd expect the treatment of a set of symptoms (syndrome) to be treated according to the cause.

If BID, lack of dopamine receptors, excess gluatamate, low adenosine levels etc are the cause of the RLS bring on the iron infusions, DAs, α2δs , dipyridamole etc

This shouldn't mean that folks with 2ndry RLS shoud automatically get these.

One last thought

In order to prove a correlation between IBS and RLS, you'd have to show that significantly more people with IBS have RLS than people who don't have IBS. That doesn't prove a cause effect connection however. If there is a causal connection is it that IBS causes RLS or RLS that causes IBS.

It may be, my idea, that if there is a connection then there may be some underlying, possibly neurological or neuromuscular factor which leads to BOTH IBS and RLS, SIBO etc.

I have read a claim that taking Buscopan is associated with RLS.

No apologies for the lecture, but sorry if it appears pompous.

Just out of interest really.

A few decades ago an eminent pyschologist suggested a connection between chromosomes and criminality. His theory was that men who had an extra Y chromosome would be more likely to be criminals. Most men have XY chromosomes (one of each), some men are XYY.

A study subsequently showed that not all men in prison had XYY and that many men who had no criminal record did have XYY. In fact no significant difference.

I can't recall how he explained female criminals! (XX)

Some (men?) have XXY. Didn't you know that's there more than 2 genders?

I prefer not to say.

[Hidden in reply to Hidden]

A bit off topic but as someone who is fascinated with genetic and marvelous combinations and permutations that make each of us unique, your post was of interest to me.

I remember, before marriage equality was acknowledged by the US Supreme Court, there were some states that were proposing legislation that people being married have genetic testing and that someone that had an XX sex chromosome pattern could only marry someone with an XY sex chromosome pattern and vice versa. No one with an XX could marry another XX or XY could marry another XY.

What was forgotten was that igenetics is not always that clear cut. It is estimated that 1% of our population does not fit the standard XX or XY pattern. They are called intersex individuals. There is XXX, XXY, XYY and XYYY and X0 out there. Also sometimes, due to other gestational errors someone can be born with a mix of male and female sex organs or an XX can appears as a man or an XY can appear to be female or someone may be born one gender but feel their (if you will) soul is that of another. I always wondered who they were supposed to marry. The definitions assumed that we were all either XX or XY and that left out intersex people out of marriage all together. Fortunately, there were debated but not enacted and the 2015 Supreme Court decision allowed for one person to marry another person without respect to their gender identity or lack of clear gender identity.

Sorry to be a bit off topic, but I wanted to help educate people out there as this is not widely know and was something that we health care workers have had to learn to process and deal with for the betterment of patient care.

[Hidden in reply to Hidden]

Thanks for your interesting response. You may be aware that where anubody has more than one X chromosome, the "extra" ones become redundant (at least as regards gender), so XO, XX, XXX, no great difference. It's that little Y chromoome that begins to stir things up.

Interesting that what you say about the supreme court has political implications. I observe that intolerance of the "diversity" brought about through genetic, gestational and hormonal variations over which people may have no choice, is greater in societies dominated by more right wing ideologies.

Such political conservatism. is also associated with religious conservatism.

Note the countries where homosexuality and gay marriages are illegal, where transgenderism isn't permitted.

Worrying, since societies don't seem.to learn from history and right wing ideology is growing in the world, even in countries that claim they're democratic.

[Hidden in reply to Hidden]

The X0 sex chromosome type does come with some unfortunate symptoms. It is called Turner's Syndrome. I took the issues with Turner's Syndrome directly from Wikipedia.

"Often, a short and webbed neck, low-set ears, low hairline at the back of the neck, short stature, and swollen hands and feet are seen at birth. Typically, they develop menstrual periods and breasts only with hormone treatment, and are unable to have children without reproductive technology. Heart defects, diabetes, and low thyroid hormone occur more frequently. Most people with TS have normal intelligence. Many have troubles with spatial visualization that may be needed for mathematics. Vision and hearing problems occur more often."

By the way, I would like to make a plug for Wikipedia. Wikipedia had a team of volunteer editors who do fact-check items and vet their articles. They are quite up to date. As someone who will edit articles, claims need to be documented and based on fact rather than speculation, conjecture, hearsay, or memory. You may finded an inaccuracy, but rest assured that it will be corrected or removed quickly. Since things can be changed by the general public, you will find questionable information only for a short time before it removed or fixed.

An example that happened to me was that I lived in Iowa during the 09 NOV 1968 Illinois earthquake. While I did not feel it, it was strong enough to partially detach a leg on the water tower in Lineville, IA which was in my county and it began to leak about 300 gallons of water an hour. The Wikipedia article did not mention this so I added it. It was immediately removed, I thought I did something wrong in the editing process and added it again, it was removed with a note to my account that all entries must be substantiated. I contacted my local newspaper, pulled the article with details about the damage and put in a reference to the article. The changes were then accepted and still appear to this day in the article . I was impressed and have always referenced any changes I may make other than grammar or typos errors.

[Hidden in reply to Hidden]

Thanks again for the interesting info. I recall Turner's XO syndrome now and I've met a couple of people with Klinefelter's syndrome which is XXY. Males with some female characteristics.

I'm not averse to using Wikipedia or even Google. It does enable access to original sources where these are cited and accessible.