ECOPIPAM

[Joolsg]

Does anyone know whether the results of the study on ecopipam alleviating Augmentation has been published? William Ondo was doing the study.

[Hidden]

Have you tried to research it. ? Or i should say search for it.

[Joolsg in reply to Hidden]

Yes- not found anything so far. It was quite a small study- so maybe that’s why we haven’t heard anything.

[Hidden in reply to Joolsg]

Could very well be the reason. Altho they do publish small studies. Or maybe they are not ready to publish it yet. Who know's.

[Hidden]

Have done a brief search, can't find it.

I did find this though and I believe Ecopipam is D1 antagonist

sciencedirect.com/science/a...

[Joolsg in reply to Hidden]

Thanks Manerva. I suspect the trial begun in 2017 by Dr Ondo was to test if these results ( on mice) were reproduced in humans. I’ll look on the RLS foundation site to see if I can find anything.

[involuntarydancer]

I think there might have been something about it in the most recent ‘nightwalker’ magazine. I’ll have a look in the morning and post if I find anything. From memory the US rls society was contributing to the funding so there should be something on their website.

[Joolsg in reply to involuntarydancer]

Thanks Lotte. I’ll have a look on the site.

[Parminter]

clinicaltrials.gov/ct2/show...

'No results posted'.

[Joolsg in reply to Parminter]

Thanks Parminter. Maybe I should contact Dr Ondo. The trial was supposed to end in October 2018.

[Madlegs1]

clinicaltrials.gov/ct2/show...

[Parminter]

The problem with this drug, even if it does work, is that it uses one drug to deal with side-effects of another. And so on ad infinitum. Every addition will carry its own burden and unknowable interactions. That bothers me a lot.

[Joolsg in reply to Parminter]

Yep- we seem to be constantly trying to stay one step ahead but ending up two steps behind.

[Parminter]

This bunch has never been one step ahead, unless you count all the night walking.

But I do admire Doctor Ondo, and do not doubt he is doing his utmost to help us to stop this particular, undesirable nocturnal exercise.

[Sara_2611]

I dont know .apologies