Gabapentin stomach issues

[Andyroo66]

Hi

been on gabapentin (for migraine and RLS) 300mg (in the evening) a few days, I had gastritis (I think) a month ago and already I can feel the pain and discomfort coming back in my stomach and into my back.

It's rather dissapointing as the gastritis is what triggered everything to flare up in the first place

Im already on Omeprazole 20mg which I also think is aggravating RLS

Its a never ending merry go around...

Is Pregabalin better for the stomach? Any help gratefully received

[Joolsg]

I was on Gabapentin for about 4/5 months but it gave me terrible diarrhoea. I switched to pregabalin and I have found it much better. Hope that helps.

I know omeprazole stops iron absorption and low serum ferritin can cause RLS. I don’t know of any alternatives but I do have friends with stomach issues who have had good results with strong pro biotics like Symprove and VSL3.

Interestingly there is a study in the UK led by Prof Choudhuri of Kings College Hospital on using Symprove to help Parkinsons Disease.

The theory is that a leaky gut causes auto immune disease.

RLS is a disease that uses similar meds to Parkinsons ( dopamine agonists) so maybe it’s worth a try.

[Andyroo66 in reply to Joolsg]

Thanks yes I think it's all down to my gut, problem is I think i have SIBO so probiotics seem to make me worse, tried Symprove a while back and it made me worse. Took some LP229V last nite as an experiment and Im definitely worse this morning with bloating and stomach pain. Will speak with my neuro about maybe switching to Pregabalin

[DicCarlson in reply to Andyroo66]

I took probiotics (for years, many different types) stopped recently and have felt much better gut-wise. I still take fermented foods daily. Try Oil of Oregano (4 drops mixed in a carrier oil) for SIBO. Here's a website, search "SIBO, Oil of Oregano" for more sibosurvivor.com/oregano-oi...

[Andyroo66 in reply to DicCarlson]

thanks wll do which brand do you buy? are you in UK?

[DicCarlson in reply to Andyroo66]

I am in the USA. I used Zane Hellas and put 4 drops on a tablespoon and mixed it with MCT Oil or Olive Oil. Beware - it burns a little, just follow it with a little tea or coffee.

[AntoinetteS]

Hey, I totally get how frustrating this must be. I’ve been on Neurontin (Gabapentin) from this trusted pharmacy - world-delivery-service.com/... for RLS too, and it’s been a game-changer for my symptoms, but stomach issues can be such a pain—literally. Since you’ve had gastritis before, Gabapentin might be irritating your stomach lining, especially if you're prone to acid issues. Some people find that taking it with food or a glass of milk helps reduce irritation. Also, spacing it out from your Omeprazole might be worth a try, since PPIs can sometimes mess with digestion in unexpected ways.

As for Pregabalin, some people do report it being gentler on the stomach, but it really depends on the person. If Gabapentin is working well for your RLS and migraines aside from the stomach issues, maybe trying a lower dose split throughout the day could help? Definitely worth discussing with your doctor to see if an adjustment or switch makes sense for you. Hope you find some relief soon! 💕