Slides from Dr Naviaux illustrating the proposed metabolic effects of a cell danger response on mitochondria.
Self Defense : Slides from Dr Naviaux... - Ramsays Disease
Self Defense
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Slides simplify an explanation of Dauer state written in the research journal.
Dr Robert Naviaux has suggested a three phased model for reversing the cell danger response (CDR), and recovering ME/CFS patients from a dauer hypometabolic sta
The Naviaux Protocol
Remove the trigger. This would presumably mean treating any underlying pathogen (antivirals, antibiotics), treating autoimmunity or autoinflammation (immunosuppressants), unbinding toxins (metals, mold), or avoiding certain environments (mold, chemicals, etc).
Refill the metabolic tank. Naviaux specifically implicates NAD+, NADPH, Glycerol, and Citrulline as key metabolites that rise when nematodes (C. elegans) exit hypo-metabolism (See slide below). On the CDC call he also mentioned that there are hundreds of others that his research data is identifying.
Flip the switch. Naviaux mentioned that he's raising funds for a low dose trail of a drug called suramin in ME/CFS patients. Suramin is an IV pharmaceutical used in African sleeping sickness.
In practice this protocol might look something like:
1 Rituximab
2 Various supplements
3 Suramin