Lupron: Be very careful – in that if... - Prostate Cancer N...

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Lupron

Teddski profile image
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Be very careful – in that if you have any heart problems, make sure you have regular appointments with your cardiologist. I have a replaced Mitral heart value which is stainless steel valve. The Lupron damaged my heart – in a regular heart beat 85% to 90% of the blood is pumped thru the heart with every heat beat. After being on Lupron for 18-months, the percenrage of blood flow through my heart was at 43%. Total heart failure is determined when it reaches 40%. I had major difficulty walking and going up stairs, I needed to slowly take one step at a time. Thankfully, when I stopped the Lupron, my heart returned to normal. My prostate cancer has returned and am on Orgovyx daily. The doctor wanted to restart the Lupron and I told him “Absolutely Not”

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Teddski profile image
Teddski
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Stellabell profile image
Stellabell

I was told that 55 to 60% was a normal ejection fraction. You are correct about Lupron, however. My heart function also dropped when I was on it for two years.

Lezzers profile image
Lezzers

HiYour EF number is the rate the blood is pumped out of your heart with each contraction. A normal EF is between 50 & 75 (there are slight variations to this number depending on where you live) you never have an EF of 100% as this would mean there would be no blood left in your heart to be pumped out. Equally an EF of over 75 would also be concerning & need investigating. An EF of 40%, would not be considered total heart failure. (HF)Taking into consideration those numbers, an EF of 43 isn't too bad, you would only be considered to have mild heart failure (HF) with that number, although you can still be symptomatic even with a high EF. However if your heart has now returned to normal then you have no permanent damage to it & I would think you no longer have HF?

My husband has had HF since 2012 & in that time his EF has gone from 35/40 to 30 to 51, it's currently 30/35 which is considered moderate to severe HF. His heart is permanently damaged due to a previous heart attack.

I hope this helps to put your mind as rest, although I think I would ask your cardiologist to explain this to you.

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