New to board

[Raflo]

Recently told that I mostly likely have recurrent prostate cancer. This is based solely on PSA and other risk factors (age, etc.). I have had a PET PSMA, NM Bone scan, CT Chest and Pelvis scan, and all have come out clean and clear.

Local oncologist (while admitting he doesn't really know where the cancer is) is recommending hormone treatment for 3 months, then radiation for 7 weeks, then 2-3 months of Hormones.

Second opinion has recommended me to MD Anderson for their evaluation (I live in CA, they are in TX). This opinion (prostate researcher) has suggested to me that the current gold standard in treatment would be Triple therapy of Hormone, radiation and chemo.

Third opinion, from the City of Hope where I had my prostatectomy in 2017, is to pursue a clinical trial of White Bottom Mushroom.

I'm getting more confused by the day and feel like I'm going to have to be the "general contractor".

Coming to this board in hopes of learning more about my options. I feel like I need to make some treatment decisions here in the next couple of months.

[Tall_Allen]

What is your PSA. The decision should be based on PSA.

Consider this clinical trial:

classic.clinicaltrials.gov/...

[Raflo in reply to Tall_Allen]

PSA is .55, down from .62 2 months ago, but up from .47 8 months ago and .23 1 year ago.

Thanks for passing that information on for the trial. Looks like that might be for those who had lymph node issues and subsequent radiation?

I had no hormone treatment or radiation in 2017. Only treatment was prostatectomy.

[Ramp7]

Asking questions and research are the best approach. Things have changed so much since I was diagnosed 16 years ago.

[Raflo in reply to Ramp7]

they’ve changed quite a bit just in the 6 years since my surgery

[Teufelshunde]

I thought the standard progression for BCR after prostatectomy was radiation to the pelvic area and lymph nodes. there. Whether you use ADT before/during/after was based on PSA. Over 0.50 uses ADT and under does not. Just went through this process 2 years ago. Only did one month of ADT-Do NOT get a shot. Do oral ADT so you can stop if you dont like it. My PSA undetectable now. While you are figuring this out, I would suggest taking BROQ sulforaphane (Broq.life or Amazon) as the clinical study shows it basically stops PSA progression in BCR after prostatectomy. Take the 60mg/day dose used in the study. Good luck brother.

aacrjournals.org/cancerprev...