Specially when it comes to side effects, persons having other health issues, like someone who has severe coronary artery disease (CAD).
Side effetcs:
Hot flashes - Fatigue - Loss of libido - Weight gain - Gynecomastia - Osteoporosis and bone density loss - Mood changes and depression - Memory and cognitive changes - Anemia - Metabolic changes - Muscle loss - Cardiovascular risks, heart attacks and strokes.