Finished IMRT 20 sessions 3 months Ago kishan & finished4 months Orgovyx UCLA.. Still getting up 5-6 times a night Nocturia..What to do?

[JWS13]

Imrt 20 sessions - Finished 3months ago (kishan-ucla)- Orgovyx 4 months finish tomorrow-

Still urinating 5-6 x per night.

Still taking flomax and cialis 5 mg every day but no relief.

Can I expect to get to 2 urination per night as the "burnt" prostate heals and SHRINKS!

4-3 Gleason 7- Psma -no spread - 68 - ECE-

Any suggestions would help!!! TY

P>S - Any supplements actual work?- beta sisterol- prostate plus- saw palmetto??????

[Tall_Allen]

That is the expected inflammatory response. It should be near maximum now and for the next few weeks. After that, it will get better. If you can't pee at all, go to the ER.

Get a scrip for an alpha blocker like Flomax (tamsulosin) and take 2 at night. Also take an NSAID throughout the day. Also, take 5 mg Cialis everyday - it helps you pee.

Don't take any supplements - they will make it worse because they irritate already irritated tissue. Avoid caffeine and fruit juices that stimulate the kidneys. Drink at night only if thirsty.

[LongevityAT]

I finished IMRT 20 treatments with Kishan about 2 months ago and I'm currently still on ADT. Until a week ago I was also getting up 4 - 5 times every night. Mentioned this to my Urologist and when I told him I drink 2 - 2.5 liters of water every day, he had me cut back. Now, I drink about 1.5 liter of water with the same amount of coffee and tea I was already consuming. I saw an almost immediate improvement down to 3 times per night and last night I was only up once.

So in addition to limiting your evening liquids, pay attention to the amount of liquids throughout the day. And pay attention to the color of your urine. Mine was basically clear, which it turns out is not good. Find your balance of water intake that produces a light yellow urine.

[dixiedad]

I'm taking gemtesa which I was told is supposed to relax the muscle 'around'(?) the bladder.

I also recently discovered that I have sleep apnea and am on a BiPAP machine. Now I sleep all night with no get ups. I don't know if it's the gemtesa or the BiPAP or a combination, but the night's rest is great.

[conbio]

I was there too after 24 sessions of EBRT and then brachy. VERY annoying. It is hard losing sleep. Hang in there - it will get better. Seconding TA's advice of two Flowmax at night. And of course, manage your fluid intake. I basically stopped drinking fluid at 5 pm. Mine took 4-5 months before really settling back to normal. You'll get there.

[Mike404]

I did give SBRT. No side effects except nocturia, which in my case took about nine months to full resolve. Flomax and Cialis helped.

[JWS13 in reply to Mike404]

is it fully resolved ? did you do anything special? i am taking cialis & flomax ... i lose libido with flomax...did it get progessively better within the 9 months ( i.e. like 5 months waking up 3 x a night, 7 months 2 times, etc.)

[cpcohen]

FWIW --

If drugs don't work, consider a condom catheter (= external catheter) and a "night bag" beside the bed. It's clumsy, but it'll let you pee without moving out of bed.

Ask your doc about it. There may be some good reason to _not_ use a condom catheter, after radiation treatment.

. Charles

[Mike404]

The last few months it got progressively better. I went from 3, to 2, to once per night. It takes time for the bladder to heal. I noticed burning when full. Eventually I started noticing a lack of burning. I had a bigger problem with low blood pressure from the meds. Stay hydrated.

[j-o-h-n]

Wear a double depends when you go to sleep,,,,,, Put a doubled up canvas on the bed and maybe two old towels under your bod. Place a large open mouth bottle near the bed to piss in it without going for a walk to the toilet. Keep pissing in the bottle and jump right back into bed (do all this with your lights off). Hopefully that may work for you, if not, see if there's a slightly used dick at a garage sale in the neighborhood.

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 05/27/2023 9:39 PM DST

[Golferforever]

I think that you should consult with your PCP and or Urologist. Both helped me immensely. Contributors here are not MD’s. Urologist switched me from solifenacin to Myrbetriq. He also suggested Prolief supplement to remove acid, which irritateds the bladder. Both work well. Went from 6-9 times a night to 2-3 and continuing to improve. This was after SRT which I needed after RP. Good luck..