Perioperative beta blockers and PC re... - Prostate Cancer N...

Prostate Cancer Network

5,121 members3,209 posts

Perioperative beta blockers and PC recurrence

dentaltwin profile image
2 Replies

Don't know if this has been discussed--this just crossed my desk. Non-selective beta-blockers at time of radical prostatectomy was associated with a lower risk of recurrence. Frankly, sounds far-fetched to me:

jamanetwork.com/journals/ja...

Written by
dentaltwin profile image
dentaltwin
To view profiles and participate in discussions please or .
Read more about...
2 Replies
Tall_Allen profile image
Tall_Allen

I share your skepticism. It was just a retrospective study. Other retrospective studies show added risk or no effect:

wjso.biomedcentral.com/arti...

sciencedirect.com/science/a...

bjanaesthesia.org/article/S...

ejcancer.com/article/S0959-...

The justification is that nerves innervate tumors and their signals are needed for tumor growth. There is a prospective clinical trial:

clinicaltrials.gov/ct2/show...

dentaltwin profile image
dentaltwin in reply to Tall_Allen

Really inspires confidence, doesn't it?

Not what you're looking for?

You may also like...

Gleason 8 on HRT

I was recently diagnosed with localized prostate cancer Gleason 8, which fortunately was caught...

Testosterone after ADT?

My pre-ADT testosterone was 620. Now, after four months of ADT (and radiation), it's 9. My ADT...

mr. Smith

just got diagnosed with prostate cancer with gleson scale of 8. I have had CAT scan and bone scan,...

side effects

i have prostate cancer with gleson scale of 8. Trying to figure out if radiation or surgery is the...

Diagnosed 4+3

Hello all, Yesterday I was diagnosed with prostate cancer & would appreciate any guidance....