Post EBRT/ Post ADT PSA readings

[Waldo13]

After 28 sessions and 6 months ADT my first PSA reading was <0.1. Three months later the reading is 0.1. Does this constitute a rise or is it insignificant?

[Tall_Allen]

He has a prostate, so he should have some PSA as his T level rises.

[Magnus1964]

I don't think it's significant. At that level you will get some small movements in PSA do to irritations or inflammations in the prostate bed.

[ADTMan]

Look at this which was recently posted on this site: ncbi.nlm.nih.gov/pmc/articl...

The explanation seems to me to be that the persistence of PSA over .9 indicates the degree of castration-resistant cells remaining after RT. A recent PCRI video on Youtube discusses this as well. I would strongly urge you get a PSMA scan, even at that low PSA because castration-resistant cells do not produce PSA but still can be seen on a PSMA scan.

[Hidden in reply to ADTMan]

you mean over .09, not .9. Which would basically be something pretty close to where he is. If i'm not mistaken that study also used the figure of 95% drop being good and also said >.5 is a negative threshold.