Split dosage for residual PMR pains: Hi Looking for... - PMRGCAuk

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Split dosage for residual PMR pains

Verwood profile image
7 Replies

Hi Looking for advise on possible effect of splitting my Preds dosage.

I have had a great reduction in pain and stiffness but still have mild pain in my right shoulder in the morning, and this continues till about 2 hours after taking my Preds.

Has any body had any success with similar residual pains by splitting the dose., i.e 75% in the morning 25% late night. Ask the doctor and he said give it a try. but don't want to try if I am risking a relapse, any advise would be most welcome.

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Verwood profile image
Verwood
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7 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

Usual recommendation is 2/3rd am, 1/3rd pm - that way you have the residue from the evening’s dose to help before the morning one kicks in.

But to be honest the initial dose (which I guess you are still on) should be giving you better relief - unless you are one of those patients that -

a, doesn’t get full benefit of dose either because it doesn’t last 24 hours, or you body doesn’t metabolise it as well as others - or

b. you are still trying to carry on as normal.

I don’t want to discourage you to try a new way, but personally I would want the protocol you’re on to be controlling things without having to fiddle with timings.

But of course it’s your choice, so try splitting and see if you get a better result - if so, then good. But please don’t consider tapering until you have symptoms controlled.

Verwood profile image
Verwood in reply to DorsetLady

Hi DL,

Doctor was of the opinion that I may be metabolizing the Preds fast, as I am only 56 and 6ft 2inch tall and reasonable fit and well as he said ( except the PMR )

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply to Verwood

Yes that could be true.

Well it’s worth giving it a go - what worked for me, or works for anybody else on here doesn’t necessarily mean it will work for you - or vice versa.

So you won’t know until you try - so try and see...and let us know please....and good luck!

PMRpro profile image
PMRproAmbassador

It works for some people and may save them upping the dose to manage returning pains. As DL says, 2/3 and 1/3 is a common split but everyone is different. It is because the antiinflammatory effect lasts between 12 and 36 hours depending on the person - if you are towards the 12 hour end the pain will start to return inside 24 hours.

You may have to experiment a bit to find the ideal for you.

Verwood profile image
Verwood in reply to PMRpro

Thank you for your advice will give it a try for a few day let you know the results.

_multistrada profile image
_multistrada

I always split mine am pm it helps a lot

Alebeau profile image
Alebeau

I have been splitting my dose for 7 months now - best thing I ever did. Pain free all day and night. I take half in the morning and half at night.

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