Omeprazole chest pain: I have been taking... - PMRGCAuk

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Omeprazole chest pain

GaryWW profile image
17 Replies

I have been taking omeprazole for about 6 months. Recently I started having minor chest pain. Uncomfortable but not bad. Wakes me up at night and have it sometimes during the day. Went off omeprazole 10 days ago and no longer have the pain. But the GERD is back. Should I try one of the other meds for GERD?

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GaryWW profile image
GaryWW
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17 Replies

They actually recommend you taper but also add in something like Ranitidine or Zantac but you should mention this to your Doctor.

You can definitely get rebound acid production if you stop Omeprazole suddenly.

GaryWW profile image
GaryWW in reply to

Yes. I understand. I was more concerned with the chest pain while taking the omeprazole

I agree with mrs nails add some Ranitidine to help with the rebound reflux. Have you had the chest pain checked out? I was on lanzaprozole from 2001-2018. I stopped dead, realised that wasnt a good idea so i alternated days with lanzaprozole and Ranitidine. If you add something to deal with the reflux it should ease. I put a book under each "leg" at the head of my bed to raise tbe top of my body. That helped. Also, just check your diet. White bread, green sweet peppers, the skin of cucumber give me severe indigestion and chest pain. I am sure i will identify other foods that irritate my system. Otherwise, at least get chest pain checked if it was severe enough for you to stop meds.

SnazzyD profile image
SnazzyD

For me Omeprazole made things worse as well as feeling peculiar. I went on to Ranitidine, much better but got rebound acid two weeks later. Ended up on Enteric coated Pred plus Gaviscon at night.

You do need to stop PPI’s gradually to avoid rebound acidity. This page is quite interesting

ueg.eu/education/latest-new...

in reply toSnazzyD

Thanks for that SnazzyD, a very helpful and informative link.

miss-philosopher profile image
miss-philosopher

Yes, Enteric coated Pred and Gaviscon sounds like a good idea. I buy empty gel capsules and put the pred tabl in. It helps a lot.

GaryWW profile image
GaryWW

How long should I wait from when I stop omeprazole to start a different PPI?

in reply toGaryWW

Do you mean using Ranitidine or similar instead of ppi? If you do you can take you can take gaviscon/Ranitidine as soon as ppi stopped. If you take it because you have uncoated pred, is it possible to get enteric coated that pass through gi tract before they disperse pred? If you can only get uncoated you can use antacid straightaway as far as i know.

As i said before, i used ppi and Ranitidine alternate days you to ease rebound reflux when i was tapering ppi . You are trying to avoid rebound reflux and future issues of gerd. I find now (1yr on), that i dont need daily Ranitidine. I take as required.

GaryWW profile image
GaryWW in reply to

I mean going from omeprazole to lansoprazole or pantoprazole

in reply toGaryWW

As far as i can see you can change ppi, but has dr/you explored other forms of control? I have provided this link. In table 1 it says a "red flag" about ppi use is radiating chest pain. It says medical assistance should be sort as a matter of urgency.

pharmacytimes.com/publicati...

PMRpro profile image
PMRproAmbassador in reply toGaryWW

They are all PPIs - they are likely to cause similar problems. Which surely is hardly the point.

4840 profile image
4840 in reply toGaryWW

I was told by my GP to take Omeprazole every other day for a week, then start Zantac (Ranitidine) 1/2 tablet twice a day (morning and night) in order to avoid a rebound.

RolyB profile image
RolyB

I was on omeprazol initially but they made feel nauseous. I changed to lansoprazole and have been fine on those.

GaryWW profile image
GaryWW

Thank you.

Odosmum profile image
Odosmum

I take Lansoprazol. The regular dose of 30 mg gives me quite bad pain, like heartburn. Cutting it to 15 mg twice a day, makes a huge difference.

PMRpro profile image
PMRproAmbassador in reply toOdosmum

That's worth knowing!

Dream21 profile image
Dream21

I just switched from Omeprazole to Rantidine (Generic for Zantac). The pharmacist felt this was a better drug and tolerated better by the body.

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