I am currently on Prednisolone for GCA and have reduced to 4mg/day. However I am struggling to reduce any further. My Rheumatologist has suggested that I could try switching to Methotrexate to wean off the steroids but I am concerned about the possible side effects of Methotrexate.
Does anyone have relevant experience or comments?
My history with Prednisolone is that I was initially prescribed 40mg/day due to temporal pain symptoms that indicated GCA. The symptoms disappeared within 24 hours of starting the Prednisolone. After 3 months I had tapered the Prednisolone to 10mg/day but at this level, I re-experienced temporal pain and the Prednisolone had to be increased back to 40mg/day. I restarted tapering and after a further 3 months was down to 7.5mg/day. After a further 3 months I was down to 5mg/day and after a further 3 months was down to 4mg/day.
However, over the last 6 months I have struggled to reduce further. I cannot seem to reduce further but experienced temporal pain when tried “reducing from 4mg/3mg alternate days to 3mg daily