Hi, has anyone been involved in a drug trial? My consultant is keen for me to participate. Any info would be appreciated. Thanks Michelle

[MickeyMouse]

[Hidden]

I am on the East coast of US. No trials here. I keep looking.

[Hidden]

Hi MickeyMouse, do you know what the drug is that you will be trialling?

[MickeyMouse in reply to Hidden]

Hi, I dont know if my consultant has a specific trial in mind. He is keen for me to participate due to no improvement of my LFTs on Urso and severe itching.

[Karaliz]

Hi Michelle,

I hail from Melbourne, Australia and was recruited into the Obeticholic Acid trial December 2012. This aims to see an improvement in LFTS when taken in conjunction with Urso. It is a double blinded trial so neither the investigating doctors nor I know which of the three arms of the trial I am in. i.e there are 2 active arms- 5mg and 10 mg and a placebo arm.

Like you ,my consultant was keen for my involvement as I am part of a minority who has not really responded to Urso. Have been on Urso fo nearly 10 years since diagnosis at age 38.

My consultant and I suspect I am either on the placebo or OCA is not working for me as LFTS are slightly worse if anything !

However , trials are for the greater good so the final results are worth focussing on.

I gather I am only one of a handful of Australians on this trial as it had nearly closed by the time it made its way Down Under !! Mostly Europeans taking part I believe ?

Hope this helps a little, Michelle.

[MickeyMouse in reply to Karaliz]

Hi Karaliz, thanks for the reply. It's a shame this trial is closed now as I also don't really respond to Urso. Fingers crossed that some good comes out of this trial and you were on the placebo. Take care.

[Karaliz]

My sentiments exactly. Apparently the preliminary, smaller trials of OCA were very favourable so that is comforting. Which drug trial is your doctor wanting you to participate in ?

Take care and hope you're feeling ok.

[MickeyMouse in reply to Karaliz]

I dont know. If there is one, it may be for the severe itching! Pleased to hear the preliminary trials were good. Keep me informed of the results of yours,Thanks.