doe's anyone speech become slurred wh... - Pernicious Anaemi...
doe's anyone speech become slurred when your B12 is due to be injected?
no never had that.i have extreme tiredness and numbness in hands and feet.my memory is not good and concentration goes.
Have only just been diagnosed with PA the onlysymptoms I get are tiredness. Brain fog pains in my legs and tingling and pain in my hands, not heard of slurred speech but anything is possible with PA
Hi, please make sure that you are being treated for PA in accordance with the British National Formulary especially if you have neurological issues as above in mummytina's psot
This part of what it says; please note that many people find being treated in accordance with the first paragraph still does not deal with their problems, and it seems many doctors ignore the implications of the second paragraph.
"By intramuscular injection, pernicious anaemia and othe macrocytic anaemias without neurological involvement, initially 1 mg 3 times a week for 2 weeks and then 1mg every 3 months.
Pernicious anaemia and other macrocytic anaemias with neurological involvement, initially 1mg on alternate days until no further improvement, then 1mg every 2 months."
Doctors seem repeatedly to completely misinterpret the second paragraph and ignore the fact that many of their patients have neurological involvement and after the six loading doses just inject 1mg every 3 months. This is not correct, when neurological issues are present doctors should be treating according to the second paragraph quoted.
You can consult the BNF online:
Sign in etc as instructed then you can have about half an hour on the site; you can even print what you neeed: go to Section 9.1.2 Drugs used in megaloblastic anaemias.