What are some signs that you need mor... - Pernicious Anaemi...

Pernicious Anaemia Society

32,181 members23,350 posts

What are some signs that you need more injections as opposed to it being reversing out?

QianYunxi profile image
14 Replies

I recently switched from cyano to methyl and I have been doing EOD, the main neurological symptoms I have left are muscle weakness and shortness of breath(anaemia like feeling).

I get panic attacks whenever I hit 24 hrs after the last injection (thankfully they are less severe now).

Before I would get a more full blown panic attack, now I just get the anxiety and impending feeling of doom when it wears off and the muscle weakness returns although slightly less pronounced.

Is this a sign that I should be doing it every day?

Written by
QianYunxi profile image
QianYunxi
To view profiles and participate in discussions please or .
14 Replies
Nackapan profile image
Nackapan

Is your iron znd ferritin level okay .Vitamin D ?

If your reactions are worse on methylcobalabin.

Some have reported this .

Go back to cyanocobalamin .

Only you know how you feel.

EOD sounds as though plenty .

Just keep going with a regime that is bearable.

Then try every 3rd day .

Thd symptoms you describe are familiar.

Your whole nervous system on over drive.

Your autonomic system in overdrive.

'Fight or flight'

Feels like a panic attack but nothing to panic about .

Apart ftom health fear.

Breathing exercises to stay calm helped me .

Also some drugs calm the nervous system if needed.

Hope fully will improve soon.

It sounds like early days .

You dong mention time frame of b12 deficiency

QianYunxi profile image
QianYunxi in reply to Nackapan

My ferritin is at 44 beginning of this month, and haven't checked vit D, but recently realized that the 5000iu I was taking everyday was inadequate.

I have been on cyano injections since last year August.

After making this post, I ate something salty and the muscle weakness and breathlessness went away.💀💀

I don't know why every time I take B complex my sodium gets drained, and every time I think it can't be sodium it is.

Thanks for assuring me the panic attacks are normal.

At first I didn't even realize that they were, and thought I must be doing something very wrong with electrolytes or iron/cbc.

Nackapan profile image
Nackapan in reply to QianYunxi

I've read up to 4000mcg vit D daily. MaxUnless prescribed as a loading dose

I take 1-2000mcg vit D daily with vit K2 as a maintenence

Depends on your last blood test and level.

MarvelDC profile image
MarvelDC

a ferritin level of 44 is very low, anything below 70ug and you can start experiencing symptoms, your ferritin level will definitely be a contributing factor to your anxiety, breathlessness and muscular weakness, I’d get an iron panel done if I was you

MLJ2024 profile image
MLJ2024

Hi QianYunxi,

Oh my! Your post, although asking questions, has just answered a lot of my own 😊 I have suffered with severe panic attacks since 2003. Over the years, I was told it had nothing to do with my ferritin level. My level never seems to get above 20 and was told it was just ‘slightly’ low and couldn’t cause panic attacks. When you described the breathless (anemia-like) feeling and weakness, that’s always what I felt immediately before a full-blown attack.

My ferritin levels are still extremely low despite taking methyl B12 with iron tabs, but oddly enough since taking Vit D, K2 with magnesium, I haven’t had a single panic attack! I had no idea why. I didn’t know there was a Vit D connection with panic attacks. Also,, you mention the salt. I had a low salt diet before and was advised to increase it, so now I wonder was it the salt and Vit D that helped? My iron level never changes, so must be that

QianYunxi profile image
QianYunxi in reply to MLJ2024

Vit D increases absorption of iron through hepcidin transport. K2 improves absorption of calcium into the bones and magnesium improves absorption of vit D.

Low ferritin and low calcium can cause panic attacks, vit D helps with both. Even low vit D itself can cause panic attacks.

I suggest you watch Dr Berg's videos on yt about vitamin D, they're very informative.

Also according to the iron protocol, they have a site and fb group, ferritin should be at 100 for you to feel at your optimum.

I'm glad this post was able to help you in some way.

MLJ2024 profile image
MLJ2024

Thank you, QianYunxi, I really did find it helpful. So strange you mentioned Dr Berg as just last night I watched one of his videos on vitamin D (23 weird symptoms of deficiency) With my ferritin never going over 20, no wonder I feel so yuk! I’ll continue with what I’ve been taking and make sure I never run out of my vit d/K2 /mag combo. I hope you find the answers and solution to your health issues 🙏

QianYunxi profile image
QianYunxi in reply to MLJ2024

That's such a funny coincidence!☺️ I actually seem to have found the issue to why I may be experiencing the numbness. It seems like I have been taking too much B6 which can cause peripheral neuropathy too. If you search for signs B6 toxicity it will come up as a symptom.

Apparently, when you get too much B6, the body stores it in the muscles and then nerves and it acts like a neurotoxin.

I stopped taking my high B6 supplement 2 days ago and I can already see significant improvement. It's said that the detoxing process can take 1 month to few more for recovery.

Technoid profile image
Technoid in reply to QianYunxi

How much B6 were you taking?

QianYunxi profile image
QianYunxi in reply to Technoid

150mg. I was taking this much because there's research that shows it helps with PMS at this amount.

But I have read some people who have have had problems with this even at much lower doses as long as it was above the RDA.

Moreover B6 is already easy to find in food.

Technoid profile image
Technoid in reply to QianYunxi

Thats significantly higher than the US and EU tolerable upper limits - why take this kind of dose since its not demonstrated to be safe? Neuropathy has been observed at 100mg and EFSA recently revised their limit much lower. For your own sake please be careful and get your information from trusted sources. With regard to other posts here, Dr.Berg is not a good source of nutrition information - please check my bio for some tips on better sources.

QianYunxi profile image
QianYunxi in reply to Technoid

Yes, it was a very bad decision.

Fyi, Dr Berg wasn't the one who suggested this amount.

This was one of the articles I read: ncbi.nlm.nih.gov/pmc/articl...

Technoid profile image
Technoid in reply to QianYunxi

Thanks. It's important not to jump to conclusions based on single studies or reviews claiming effectiveness or safety of a specific dose or treatment.

Upper Limits are set conservatively for safety and exceeding them involves risk which is best approached with the guidance of a registered dietitian if possible. The US National Institutes of Health and European Food Safety Authority (and similar bodies on other regions) set "tolerable upper limits" which are a safe high end of intake for most people. These are not based on single study but on a review of all the available evidence.

Although they are not perfect or infallible, if you do plan to exceed such limits you should understand you are taking a risk and may experience adverse effects. With B6 one of those adverse effects is neuropathy. Neuropathy that is not treated quickly enough may not fully reverse so this is not a risk you should take lightly without full understanding, purely for your own health and safety.

Be well :)

QianYunxi profile image
QianYunxi in reply to Technoid

Thank you for your concern. God bless you!🧡

You may also like...

More frequent injections needed

I wasn't anaemic and they couldn't give more injections without repeat bloods. I left the surgery...

Signs you are due a B12 injection?

those of you that take vitamin B12 injections regularly, what signs does your body give you that...

Think I May Need More Injections?

I was feeling, it was amazing like I'd had the switch turned back on! So it has now been four weeks

Did anyone else feel some heightened symtpoms, and feel really down while 'reversing out?'

Especially GI, joints all clicking and popping and such muscle aches and pains, internal...

started self injecting and just need some feedback please.

started self injecting for the last 3 days with Methylcobalamin. Was advised to inject 1ml for 7...