PA trivia- did you know that PA begins years before an actual diagnosis? I read in an article about Mary Lincoln Todd- President Abraham Lincoln's wife suffered from PA and died of it since B12 had yet to be discovered. She had a history of chronic canker sores in her mouth which is reported to be a symptom of PA. I have PA and I had canker sores for years. I tried everything to ameliorate them- stop eating citrus, better oral care, etc. but they persisted until I started taking the B12 injections. No more canker sores!