Tired all the time: I've had my loading... - Pernicious Anaemi...

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Tired all the time

jomorgan1605 profile image
6 Replies

I've had my loading doses, I am having my next one in 3 weeks, however, I am so tired and aching, do I need my next dose sooner?

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jomorgan1605 profile image
jomorgan1605
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6 Replies
clivealive profile image
clivealiveForum Support

How many and at what interval were your loading doses jomorgan1605 ?

What is your diagnosis/

Do you know what your Folate level is?

Are you in the U.K.?

jomorgan1605 profile image
jomorgan1605 in reply to clivealive

Was diagnosed in may this year, had six loading doses, never got told my folate, Dr said it was low but needed to sort out my B12 level first! I'd never heard of PA before bit of a shock to the system? Yes uk

jomorgan1605 profile image
jomorgan1605 in reply to jomorgan1605

Had six loading doses over two weeks

clivealive profile image
clivealiveForum Support in reply to jomorgan1605

According to the NICE and BNF guidelines if you are having neurological symptoms your loading doses should continue until there is no further improvement.

Folic acid is important as it and B12 help your iron make red blood cells.

Go back to your GP with a list of symptoms and ask for a continuation of injections.

It is not an overnight cure and a lot will depend on how long you have had the P.A and the amount of damage it has caused.

I'm not a medically trained person but there are others on here who will be able to give you good advice.

Gambit62 profile image
Gambit62Administrator

although it is correct to start treatment for a B12 deficiency before treating a folate deficiency the time delay is 24-48 hours, so if you are still folate deficient that needs to be addressed - otherwise your body won't be able to use the B12 properly as it needs both B12 and folate for a lot of processes.

clivealive has covered the departure from recommended protocol, assuming you are UK based.

jomorgan1605 profile image
jomorgan1605

So I've been back to the drs with all my information symptoms etc she dismissed it all saying I could only have an injection every three months, said she thought I was menopausal!! Took blood test for that, I'm feeling so crap, tired and aches all the time, at my wits end now

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