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Pernicious Anaemia Society

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can't find my saved information to present to doctor

Justified profile image
5 Replies

i had saved some posts to print out for my doctor regarding neuro symptoms to be treated with loading doses until no further improvement and lso regarding symptoms to be treated regardless of levels after injections but can't find them

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Justified
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clivealive profile image
clivealiveForum Support

Treatment of cobalamin deficiency

Current clinical practice within the U.K is to treat cobalamin deficiency with hydroxocobalamin in the intramuscular form outlined in the British National Formulary, BNF,

Standard initial therapy for patients without neurological involvement is 1000 μg intramuscularly (i.m.) three times a week for two weeks.

The BNF advises that for Pernicious anaemia and other macrocytic anaemias patients presenting with neurological symptoms should receive 1000 μg i.m. on alternative days until there is no further improvement.

However, the GWG recommends a pragmatic approach in patients with neurological symptoms by reviewing the need for continuation of alternative day therapy after three weeks of treatment

Justified profile image
Justified in reply toclivealive

Thank you very much. Copied and printed :)

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PAS-adminPartner

Have a look in our Pinned Posts on the right (or down the page on mobile). Lots of pages and links in there.

Sleepybunny profile image
Sleepybunny

Google "BCSH Cobalamin and Folate Guidelines".

page 8 has details of UK b12 treatment including for those with neuro symptoms.

Page 29 is a diagnosis flowchart showing recommended process for UK doctors to follow with someone who has B12 deficiency. It mentions treatment for those with neuro symptoms

fbirder compiled a summary of mainly UK documents that might be useful. link on his profile page and in third pinned post.

BMJ B12 article

bmj.com/content/349/bmj.g5226

See point 1 in next link

b12deficiency.info/b12-writ...

Justified profile image
Justified in reply toSleepybunny

Thank you so much. have printed out what I need from this :)

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