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Help with test results

1lolabear profile image
12 Replies

Please could please be able to help me with these result? Thanks

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1lolabear profile image
1lolabear
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12 Replies
hunny59 profile image
hunny59

Hi 1lolabear - there will be others along to comment on these shortly - there was lots of good advice given in response to your last post.

Your TSH is raised and your T4 is at the bottom of the range so it may be that your thyroid is contributing to your symptoms. Unfortunately, GPs in this country tend not to take any thyroid problems seriously until your TSH is over 5 and even then it's difficult to get them to listen. You may want to take a look at the symptom list on the Thyroid UK website (link given below). The site has lots of useful information on there and they also have a forum on here which is pretty busy and you can gain a lot of information from there.

thyroiduk.org.uk/tuk/about_...

Your folate and ferritin are also both low in range and you could do with supplementing both to boost your levels. Good levels of both are required for B12 to do its job properly.

1lolabear profile image
1lolabear in reply to hunny59

Thank you for your reply. I feel I am hitting my head against a brick wall with the GP

hunny59 profile image
hunny59 in reply to 1lolabear

Oh there is plenty of room on *that* particular bandwagon for you here! I was going through exactly the same thing 12 months ago and realised pretty quickly that my GP was worse than useless. I ended up going down the self medication route after spending a lot of time reading and researching and I haven't looked back since.

1lolabear profile image
1lolabear in reply to 1lolabear

Hi, would you have any recommendations in what supplements to get please?

Gambit62 profile image
Gambit62Administrator

B12 levels aren't great - certainly in grey range where significant numbers of people have strong clinical presentation (symptoms) even though the majority of the population would be okay at those levels ... and the normal range is just set by reference to the majority of the population.

clivealive profile image
clivealiveForum Support

Hi 1lolabear If you look back at my yesterday's reply you will see I quoted "However, it appears that these markers demonstrate B12 deficiency primarily in patients whose serum B12 is in the "gray zone" (a serum B12 result between 200 pg/ml and 450 pg/ml). We believe that the "normal" B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebral spinal fluid (CSF) below 550 pg/ml"

Your serum B12 test result shows 222ng/L with a range of 180 to 900 so you are very much at the low end of the scale the "gray zone".

Sadly I don't know the difference between the American pg/ml and your ng/L but I've no doubt someone more qualified than me on here will be able to explain.

1lolabear profile image
1lolabear in reply to clivealive

Thank you very much for your reply. It is very informative. I now have the battle of trying to get injections 😩

solarised profile image
solarised in reply to clivealive

222ng/L = 222pg/ml ....... I'm no more qualified than Clivealive but definitely know a thing or two more than my Doctor.

fbirder profile image
fbirder in reply to solarised

222ng/L = 222pg/ml

Ah, the joys of the metric system.

I've no doubt that we'll soon be abandoning that (we don't need no bloody foreign nummers). So, in preparation for that here are some conversions into the new units -

200 ng/L = 200 pg/mL =

14 millionths of a grain per gallon =

29,405 oz per cubic mile =

76 scruples per acre-foot.

clivealive profile image
clivealiveForum Support in reply to fbirder

I thought William Shakespeare wrote "Measure for Measure" fbirder :D That is excruciating....

helvella profile image
helvella in reply to fbirder

Then again some parts of the world use pmol!

As Wiki says:

Serum vitamin B12 tests results are in pg/mL (picograms/milliliter) or pmol/L (picomoles/liter). The laboratory reference ranges for these units are similar, since the molecular weight of B12 is approximately 1000, the difference between mL and L. Thus: 550 pg/mL = 400 pmol/L.

1lolabear profile image
1lolabear

Hi all , following on from the results above, I went back to the Dr's, wanting more of an explanation. He said even though the vitb12. Is borderline, the other combined results Liver test and the hemoglobin are normal . So no cause for concern arrrrrrrgggggg

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