So I have had three-monthly injections for my PA for about a year, and every time I have one I feel really crap for about 24 hours afterwards - tired, fluey, nausea etc.
Have looked on a lot of forums but no one else seems to get this! Anyone of here have similar issues?
Thanks in advance!
Funnily enough I feel like this now after self injecting 2 hours ago. Don't normally have this response. I'll be interested to hear if others experience this too. Hope you feel better soon. 
It has actually been mentioned a number of times on this forum. Its not common but it certainly isn't unique.
It could be an interaction with something in the medication. It is more common for people to have acne type reaction though these usually get better with time ...
A lot of the things we associate with feeling ill - even fever - can be the immune system fighting infection so it may be that the B12 puts your immune system into overdrive for a short while but then calms down after 24 hours. Not sure if anyone who experiences the symptoms you mention has noticed it tailing off with time - sure they will respond.
Yup. I used to feel rough from 18 to 36 hours after a jab. It stopped after about 6 months.
I'm like this too.. But with thyroid low d iron and folate it's hard to know what this is...I feel very despondent as I've even thought of quitting si as I'm nearing the end of the loading doses plus 4 the GP has given me... Then I vow to give it 6months... It's hard as most talk of how much better they are doing after injections... I guess we should both carry on for a set period in our own minds... Hugs 😊
Know how you feel Scorpiojo. I'm still waiting to start feeling better following self injecting. Like you, I have low iron, vitamin d, and also calcium. It's all such a pickle.
On the basis that B12 can't do me any harm but not having it if I need it can, then I'm going to carry on and keep everything crossed.
I've seen posts before where people have said it took many months before they noticed any real upturn. I guess it depends how long you have been deficient and we're all different!
Hope you get that eureka moment soon.
Take care x
Aw thanks everyone. Sorry to hear you guys have trouble too, but it's reassuring to know I'm not alone. Thanks again!
That's it... If we didn't have others in the same boat it would be worrying and lonely... Hugs
I get the same, achy, fluey and if I sit I sleep, very suddenly and with no warning. A bit dodgy if I have a cuppa in my hand. One injection actually made me so bad tempered, I was literally evil for about a week.
Me too and I've been having B12 injections for 45 years. Peaks and troughs I call it.
Hi Bumblebee90. I'd be interested to know what you are injecting and where you got it from?
Hope you feel better soon.
I also feel a bit dodgy after an injection, anything up to about 24 hours and i've been getting them for 8 years
I have my injections done At my doctors surgery
Very intriguing how some do have problems and some don't. It would make an interesting survey to see how many of each type did different things - like supplement with folic acid/folate.
Hi Bumblebee90, yes I have the same thing. Lasts for about 24 hrs. Thought it was just me as I have only just starting 3 monthly injections. Hopefully this will pass as treatment progresses.
I have B12 every 12 week for illness and I have crappy 24 hours,, feeling sick. Headache. Depressed. Every time
Hi- I'm the same I've been getting b12 injection at my doctor's for about a year now. Had my recent one on Friday 6th August and didn't have any side effects until today (10th August) which is unusual, I'm assuming it's coming from the injection as I don't usually feel like this. But why did it take 3 days for symptoms to start?
Just had my B12 today at 5pm uk time. Hour later felt rubbish, tired , headache tummy discomfort and fell asleep. Just woke up at turned 10pm and struggling up the stairs to bed. Just have to tell ourselves it will get better. I’ve had pernicious anaemia for over forty years but B12 stopped for 6 years by stupid doctor so only been back on them for 6 months. Stick with it. Take care
I feel sick in my body after b12 injections. Just had my 4th
My Vitamin B12 test after injection 
Feeling bad after injection
B12 injection 
B12 injection. 
