New 'Threshold Theory' for PD from Pr... - Parkinson's Movement

Parkinson's Movement

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New 'Threshold Theory' for PD from Prof of Neurology at Harvard Medical School and Dr Simone Engelender ... just sharing

p-oui
p-oui

“Instead of studying how proteins move from one neuron to another and searching for compounds that prevent the ‘spread’ of aggregated alpha-synuclein, we need to study why alpha-synuclein accumulates within neurons and how these neurons die in the disease, and search for compounds that prevent the general neuronal dysfunction,” – Dr Engelender

5 Replies
oldestnewest

And the answer is.....

.....

.....

.....

Fasting !

Fasting activates autophagosomes :

ncbi.nlm.nih.gov/pmc/articl...

p-oui,

Your link is missing. Here it is:

scienceofparkinsons.com/201...

Jeff

p-oui
p-oui in reply to jeffreyn

Thanks Jeffreyn!

In the middle of the Simon's article is this gem:

"Both scientists insist that searching for treatments that slow or block the aggregation of alpha synuclein is still necessary."

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and that is what I have been writing about almost weekly on this website.

p-oui
p-oui in reply to sunvox

It is the point of my research on promising trials as well Joe

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