Another wrinkle in the sinemet saga. Three months after my diagnosis and my starting on the Sinemet I started taking Lexapro, 10 milligrams a day. My PD presents with lots of anxiety and depression and pain and movement problems but not tremor. In looking back at my journal I realize things really started to change for me after I started the Lexapro. Before I started the Lexapro I talked a lot about how I needed to get out and do more and how alone I felt and depressed and anxious. The problem was it was very hard to get out and do more when I felt like that. So, thank goodness for Lexapro!