Gene testing

[Rachael47]

Just as I was psyching myself up to ring to see what had happened to my results a letter arrived. It says 'you have and alteration in a gene valled BRIP1. This is likely to explain yourt history of ovarian cancer'. I was expecting a BRACA gene but this is a new one on me! Has anyone else heard of it?

[Katmal-UK]

Hi Rachael. Not heard of that one. Have you spoken with your nurse or Ovacome or Macmillan?Be interesting to know what they say. xx Kathy xx

[Lyndy]

Yes it's one of the newer ones they've identified Rachel... you are cutting edge!

Ask your genetic testing lab if you can have a face to face so they can explain more about it. I went to Addenbrookes who did my test and although some of the info went over my head it was really interesting and kind of reassuring xx

[85live4ever]

Hi Rachael, I am foxed by this as well. If you find out any more information let us know.

When I saw my onc last week a few of my questions was about gene testing I had done at the beginning of my treatment not for BRAC just to see why there is so much of oc in my family. I revived the same ansewer as before unless they find something you don't hear from them.

Does this mean you can be offered a Prep inhibitor?

Thanks for posting I am always interested in anything gene related. Take care Cindyxx

[Rachael47]

The letter was also to arrange for a follow-up meeting, at a place unspecified! I assume I will get another letter telling me where. I think I may try to get my daughter to come along, although that might not be practical. Good to be cutting edge. I was interested in gene testing as it had relevence to parp inhibitors, but I don't know if that is just BRACA genes. Will give further details when I get them.

[harpist_UK in reply to Rachael47]

I found this Rachael targetovariancancer.org.uk/...

Good to have the information, I suppose. Wishing you all the best for the follow-up.

[Rachael47 in reply to harpist_UK]

Thanks for that. I've been meaning to FB you for days - hope you're feeling ok on the new chemo?

[January-2016-UK]

What type of genetic testing did you undergo? Was it something suggested by your oncologist or did you arrange it privately?

[Rachael47 in reply to January-2016-UK]

I was referrred by my oncologist because of my family history. It was done by a doctor from St Georges I think, on day release to Guildford.

[dramaredgerbil]

Hi Rachel. I have had testing on 4 type genes and don't identify with any of them. I have been told by a professor that I still have familial cancer because of my family history. It still means you will likely respond to PARP inhibitors which is good news.