My wife 70 has Ovarian cancer and Auto Immune Hemolytic Anemia. After 2 cancelled surgeries and 3 cycles of Carboplatin and Tacsol her cancer too a nearing CS125 dropped to 8. . Then became resistant for the next 3 cycles.
After 1/3 of Caylex infusion extreme alergic reaction with spread of hives right chest throat constriction. (No Pre meds) Subsided with 50 mg . Benadryl The next morning at home allergies were more severe and I took her to Emergency for same treatment and 3
days of Benadryl 200 mg per day. They want to re-challenge with pre meds in 4 weeks
We are scared of the risk vs the benefit. Seems way too toxic. She is extremely weak 12 days later.