Stomach upset Methotrexate

[Fedupnow63]

Good evening hope everyone is doing as well as we can be 🤞

I have had my methotrexate upped 3 weeks ago and have had diarrhoea ever since. Has anyone else had this ?

Don’t know if it’s a side effect or not .

Thanks in advance 😊

[Madmusiclover]

It is! You can have injections instead. Ring the helpline.

[Fedupnow63 in reply to Madmusiclover]

Thank you ☺️

[gilox]

I had this problem but now have the injection, it works!

[Fedupnow63 in reply to gilox]

Thank you ☺️

[Patreece]

When first Diagnosed I wer on methotrexate 7 years down line & being on many other RA meds I’ve been diagnosed with pulmonary fibrosis caused by these meds this is incurable all these meds damage lungs please be careful n get act scan if get breathing problems shortness breath and make sure they don’t leave you 7 yrs between scans like they did with me

[Fedupnow63 in reply to Patreece]

Thanks

[cathie]

a common side effects useful comments for injections. Timing can be important I was told to take it on a Friday evening- which often meant I had to be near toilet during weekend which wasn’t great

[Fedupnow63 in reply to cathie]

Thank you ☺️

[Fedupnow63 in reply to cathie]

Thank you ☺️

[oldtimer2]

Yes it can definately upset the gut. Most people settle down, or are better on the injection. But it is an effect of the methotrexate, not just an irritant effect, so although changing to the injections often helps, in my case it didn't and I was changed to other DMARDs.

[Fedupnow63 in reply to oldtimer2]

Thank you ☺️

[Happy5]

Yes got digestive upsets easier as others have said when on injections. I was also prescribed metoclopramide for nausea. Discuss with your RA specialist nurse they can sort you something to help.

[Fedupnow63 in reply to Happy5]

Thank you 😊

[BadgerDave]

Hi - I was moved over to injections a few years ago and it did help with the sore stomach issue. I now take my MTX injection just before bedtime as I'm either going to be laid still / flat overnight, or asleep if I have stomach cramps. Seems to help me....maybe worth a try. Good luck.

[Fedupnow63 in reply to BadgerDave]

Thanks for your reply. I have been in touch with my nurse and she has agreed, with the consultant, that I can try MTX Injection to see if this elevates the problem. Fingers crossed 🤞😊