Methotrexate and Folic acid

[welsh12]

I know Folic Acid is not taken on same day and take Methotrexate around 6pm at night then Folic following day.Does everyone wait a full 24 hours before taking Folic acid. Pharmacy thinks needs to be full 24 hours but not seen this written down. Nurses have a three day wait for advice so seeing what others do. Thought Folic was supposed to help with side effects which for me seem to be after 12 hours.

[Runrig01]

Yes, wait 24hrs. I was told that the MTX depletes folic levels. If you take too early it wouldn’t be effective. I take it 6 days a week, in the evening, and high is the time of day I take my MTX

[Wobbies]

Yes 24 hours

[helenlw7]

I was told 24 hours so take my mtx at 9pm on a Monday, and my folic acid every night except Monday at 9pm.

[helixhelix]

In the States you take it every day! I used to get a MTX headache about 18 hours after injecting, ie follwoing early evening so took one then. Not medical advice of course just what I do.

[lily2003 in reply to helixhelix]

Yes, I’m in the US and my rheumy told me every day and that there’s just a difference of opinion between doctors on this.

[Seal49 in reply to lily2003]

I'm in u s too and Rheumatologist told me every day.

[MadBunny]

I was told not to take folic acid on the day I take the mtx and the day after.

[SlothSandpit in reply to MadBunny]

Same for me

[MadBunny in reply to SlothSandpit]

That was when I was on 25 mg but even though I'm now on 10 mg it's still the same. I guess it varies depending on the rheumy.

[SlothSandpit in reply to MadBunny]

They all seem to give different advice. My last Rheum had me on 6 pills a week. Now just 5.

[Gottarelax]

Yes. I take my methotrexate in the evening with the hope that I sleep through some side effects (not that I have an issue really) so to tie in with that take folic acid in the evening on the other days.

[Gilliancheche]

I do exactly the same. Never occurred to me that it might be a problem. I will take my folic 24 hours after from now on.

[Hevbellesp]

Hi when I was on methotrexate and folic and used take mine every day.x

[welsh12]

Thanks for all replies think we have consensus 24 hours after.

[Bionic1]

I've always been told to leave 24 hrs after taking Mtxte. I Take it on Mon then Weds, Thurs, Fr & Sat I take Folic Acid been doing the same way for years. Hope this is of some help to you x

[Kags1068 in reply to Bionic1]

Hi there B👋Hope you are keeping OK 🤞

Kxx😊

[KASHMIRI1]

I was told by my rheumy to take it two days before and the pharmacist two days afterwards. I chose the rheumys advice