Methotrexate side effects : Has anyone experience black... - NRAS

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Methotrexate side effects

1bozyact profile image
23 Replies

Has anyone experience black stools taking this medicine

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1bozyact profile image
1bozyact
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23 Replies
Azzure profile image
Azzure

hi I take 22.5mg injection and I have never had!

KittyJ profile image
KittyJ

No I haven’t, you really need to speak to your doctor as black stools should be checked out. Hopefully it’s just something you’ve eaten that’s made them this colour. 🤞🏻

nomoreheels profile image
nomoreheels

No, never have in 13 years, even at higher doses. It is listed as a potential side effect, in an overdose though. You are only prescribed 10 mg & taking it once a week aren't you? If that's correct it seems unlikely.

Please don't delay seeing your primary physician though, or maybe better report it to your Rheumy, whoever can see you first.

With the caveat that I’m not medically qualified. No, but my understanding is that mtx can occasionally cause side effects that may present like this. Regardless of whether it’s related to mtx, though, black stools are something that should always be promptly raised with a medical professional: it’s not always a sign of a serious problem, but it can be.

1bozyact profile image
1bozyact

Thanks for your replies, I did contact my rhemy and he advised me to see my PCP. Appointment set

nomoreheels profile image
nomoreheels in reply to 1bozyact

Good, I'm pleased. Keep us updated?

Gnarli profile image
Gnarli

I'm sure it's nothing awful but it's always good to check. Wishing you well

BoneyC profile image
BoneyC

Never in over 40 years of taking MTX.

Runrig01 profile image
Runrig01

No, been on it 6yrs and never had that issue. Black stools is usually a sign of bleeding within the gut, higher up. It needs prompt investigation, the only other med known to cause it is Iron tablets. May be coincidental that it’s happened at the same time as starting MTX. Hope you get answers soon.

Swanfull profile image
Swanfull

hi are you on folic acid? Usually take for MTX side affects. that will give you dark stools.

nomoreheels profile image
nomoreheels in reply to Swanfull

Does it for you Swanfull? I'm on 30 mg folic acid weekly & I don't have dark stools. If you do please see your GP about it.

Swanfull profile image
Swanfull in reply to nomoreheels

Hi there not black but dark 😂 I was told it was the iron content in it x

nomoreheels profile image
nomoreheels in reply to Swanfull

Ok, as long as you know why you have. 👍

KittyJ profile image
KittyJ in reply to Swanfull

I’ve never heard this Swanfull, who told you that please as I can’t find anything anywhere saying folic acid contains iron? I’ve been taking it 6 days a week for 25+ years and never had dark stools.

Swanfull profile image
Swanfull in reply to KittyJ

misinformed 😕

oldtimer2 profile image
oldtimer2

Are you taking any non-steroidal anti-inflammatory drugs like naproxen? They can cause bleeding and black stools. Should be taken seriously and you need to consult your GP.

medway-lady profile image
medway-lady

I know you've had great advice already I just wanted to say that Riveroxaban taken without food gives people bright green ones. Most alarming, and it happened in a hospital when they come round with meds and wait while taken despite being advised has to be with food and breakfast hasn't come round yet. Anyway the nurse came running when I said you'd better come and see this. Never said we'll wait again for the following three weeks. lol x

Pitbull2017 profile image
Pitbull2017

The misconceptions are that methotrexate has caused a problem if you're looking for something to blame that's okay, but in reality methotrexate lowers your bodies immune system from doing damage to your joints but you may have a problem that could be unrelated to rheumatoid arthritis but your immune system isn't firing on all cylinders, so the real cause needs to be established. HTB

Have you been drinking Guinness? It affects me in that way 😂.

1bozyact profile image
1bozyact in reply to

No Guinness for me, don't like the taste! Lol

LuzyCLL profile image
LuzyCLL

black stools are caused by upper gi bleeding. Do see your gp asap.

autumnlass profile image
autumnlass

Blueberries, blackberries give me dark stools… but by the time I’ve come along you are hopefully sorted out. 🌟🌺

LuzyCLL profile image
LuzyCLL in reply to autumnlass

it doesn’t look the same. I have had both Black tarry stool indicates an upper GI bleed

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