Hi I’m taking sulphasalazine at present but due to start Imraldi injections. How have people found the injections?

[Midnightsun20]

Imraldi

[KittyJ]

If you type that into the search box and filter for NRAS then all the posts about it will come up 😊

[Midnightsun20 in reply to KittyJ]

Thank you

[Hopefulfuture]

Yes I tried Imraldi unfortunately didn’t work for me. Now on benepali which I feel is a little better but still have swollen toes, feet, left hand up and down and knees are a right pain. Stopped sulphasalazine didn’t help me but still on methotrexate and prednisone. Good luck I hope it helps you.

[Midnightsun20 in reply to Hopefulfuture]

Thank you. I have also tried Methotrexate but had awful side effects on both the tablets and injections. I am hoping to get some relief with these injections as had to fight to get them and I am suffering with swollen toes, feet, knees and hands. Makes you feel very low.

[Shelley1701]

Ive been on Imraldi for a while and has been ok so far. They switched me from Humira because its cheaper. The problem I have is the pen itself. Instead of pinching the skin like I do with my methotrexate injections and did with Humira you have to pull the skin tight with your thumb and finger and press the pen against it and I find this quite fiddly. And also it stings like hell! The Humira had the citrate taken out which made them pretty much painless but Imraldi has it in and there's more fluid. Make sure you take it out of the fridge for about an hour before you inject. Good luck with it .

[Midnightsun20 in reply to Shelley1701]

Thank you very much for the above information. I am due to have a nurse visit on Monday to go through everything, so fingers crossed.

[rawillbebeaten]

I was switched to Humira after a few trials & tribulations. This worked well. I was not happy when I was swopped to Imraldi, purely for the cost factor. As others have said, it hurts, and more importantly didn't work as well for me. Luckily I was switched back to Humira very quickly, thanks to my great Rhumy Team.

You have to give it a try, but be prepared to fight for a chnage to Humira

Good Luck, many people have found it works as well for them

Michele x

[Midnightsun20 in reply to rawillbebeaten]

Thanks very much. It’s a minefield as I have tried quite a few different medications and have had a lot of side effects. Sometimes you do wonder if things will work and give relief.

[rawillbebeaten]

Yes, the changing nature of this condition is part of it's many challenges. I was on Enbrel for 14 years then had to switch because of negative side effects. Had to try a few different things after that and had some very tough times. Then I pushed for another anti TNF i.e. Humira. I'm now into my 2nd settled year, thank goodness. I know the roller coaster will happen again, but I hope it's a long way ahead. No drug seems to work for ever. The positive news is that there is research going on all the time and new drugs will be available in the future

I hope you find the right mix for you soon - I also take Sulfalazaline, Prednisolone and Hydroxycloraquinine. Keep ringing your Rheumatology team if things aren't working for you

Michele

[Midnightsun20 in reply to rawillbebeaten]

Hi Michele thank you for the above information and I’m pleased things seem settled at the moment for you. I was only diagnosed two and half years ago so you could say I’m still in the early stages.

[john140]

I've just started Imraldi after ceasing Methotrexate for a couple of years due to the horrid side-effects of MTX. So far I have had no noticeable side effects, even at the injection site. My RA is now quiet also. I had got to the stage that while trying to manage my RA with Prednisolone, as soon as I came off the Pred my RA came right back immediately so I am now very optimistic..

[Midnightsun20 in reply to john140]

Hi John, I hope you are beginning to feel the benefits of Imaldi. I started Imraldi last August and had no side effects but then my ALT levels kept increasing and unfortunately I had to stop it at the end of March. I was very disappointed as it was the best medication I had been on so far. I am now on Prednisolone until I receive my next Biologic. My advice would be keep up with your blood tests and I hope Imraldi works well for you.