Could it be that I've changed my antidepressent to morning?

[Jules13]

I've just realised that I still feel a bit out of it this morning and it couldn't possibly be from taking that one dose of Amitriptyline 36 hours ago.

Then I remembered I've also changed taking my Citalopram 10mg from nighttime to morning, as my nurse said the Citalopram can cause insomnia. But it can also cause drowsiness right? So god knows.

[Hidden]

Hi Jules, you’re taking a tricyclic anti-depressant (Amitriptyline) and a SSRI anti-depressant (Citalopram). I know when I switched from an SSRI to a Tricyclic, I had to “wash out”. I’m not sure they get along too well. I’d be speaking to a medico about this. Hope this helps, cheers Deb

[Jules13 in reply to Hidden]

The RA nurse was the one who prescribed it... he has my whole medication history and said the amitritylene wouldn't clash with any of them... oh dear x

[Mmrr]

Jules13, I think you need some medical advice taking two antidepressants might not be advised.

[Jules13 in reply to Mmrr]

It was prescribed by the RA nurse specialist. He looked at all my medication and said it was all fine x

[nomoreheels]

Your symptoms from amitriptyline did seem extreme but we've to consider not everyone responds well to meds. This is from Metabolic Healthcare Ltd.

Taking amitriptyline and citalopram together

Citalopram is an antidepressant of the SSRI class. Conversely, amitriptyline is a TCA. Both medications are prescribed to treat a range of mental health conditions, and both act to increase serotonin levels in the body.

If taken together without strict dosage directions, serotonin levels can skyrocket to a dangerous amount. Adverse effects can include high blood pressure, rapid heart rate, and loss of coordination - which can eventually lead to shock or serotonin syndrome (although this is extremely rare).

It’s possible that your GP might prescribe you both of these antidepressants at once. If this is the case, don’t fret. Your GP will provide directions that ensure you do not take in too much serotonin at once. This might mean you take a dose of citalopram in the morning and a dose of amitriptyline in the evening - by spreading out the time you take the medications, you’ll be greatly reducing the risk of side effects. echo.co.uk/blog/why-you-nee...

[Jules13 in reply to nomoreheels]

I only took one dose and stopped so think I'm ok x

[Joaclp]

I had a scary serotintin reaction from taking an SSRI with the migraine medication imitrex, so check with your GP.

[Jules13 in reply to Joaclp]

Not taking it after the first horrible reaction so am ok xxx