I am new to this forum. On Nov 20th I stopped taking methotrexate due to starting rituximab. I have had 2 rituximab infusions 2 weeks apart, last one on Dec 5th. My rheumy also lowered my prednisone from 15 mg to 10 mg after my first infusion than to 5mg after my second infusion. I just had bloodwork done yesterday dec 18th and my CRP is at 9.1. It was 1.2 when my prednisone was at 15 mg and on methotrexate. Just concerned the rituximab is not working. Is it to early still to see a reduction in the CRP? Should i be concerned?