Baricitinib

[linziej]

Has anyone been on this new drug? I would be grateful to hear your opinions.

Many Thanks

[Hidden]

Do you mean baricitinib? Where abouts are you in the world? In the UK NICE are currently reviewing how baricitinib will be prescribed for use in the NHS.

Beverley (NRAS Helpline)

[linziej in reply to Hidden]

Hi

Yes. My consultant wrote it down for me yesterday. I'm the uk.

[Hidden in reply to linziej]

Hi linziej,

is he going to try you on it? As I mentioned, it has only just been approved for use in the UK and NICE are currently deciding how it will be used. I'm not sure if it is used anywhere else in the world. Tofacitinib, which is also a JAK inhibitor, is used already in the States. Hopefully there will be someone on here who is on it.

Beverley

[linziej in reply to Hidden]

Hi

Yes she wants me on it. I believe it is used in other parts of the world. A bit nervous trying something so new.

[linziej in reply to Hidden]

Yes tofacitinib is her second option.

Thanks

[Hidden in reply to linziej]

keep us updated how you get on please. and hope it works for you

[linziej in reply to Hidden]

Thank you. And will do.

[carol555]

Hi, I have been on a clinical trial on this drug for 3 years or so and I definitely give it the thumbs up! I also take hydroxychloroquine, Meloxicam and Sulphasalazine- not long been on this one. I was in a bad way when I started on it so do need top ups but I do know someone who was newly diagnosed and only takes this drug on its own so definitely would recommend it. Hope this helps you and wish you only the best.

[Hidden]

Baricitinib (Olumiant is the brand name) was recently given NICE approval. It is a JAK inhibitor so not a biologic . JAK is an ancronym for th scientific term for a particular category of signalling molecules within the cell (Janus Kinases) - It was approved just this week so this is brand new news!

europeanpharmaceuticalrevie...

We are covering JAK inhibitors in more detail in our Summer NRAS Members' Magazine and there is more detail in the NRAS booklet Medicines in Rheumatoid Arthrits which we can send to you free. Just call 0845 458 3969 to order your copy of the booklet.

[linziej in reply to Hidden]

Thank you so much for your information.

[bernese1225]

Hi linziej, how are you finding baricitinib? I’m in the U.K. I’ve just picked my tablets up and starting them tomorrow.

[weymouth321 in reply to bernese1225]

Hi Bernese,

How are you finding Baricitinib ? My consultant has prescribed it for me, due to Sulfalasazine 2,000 per day no longer effective after 5 year's.

So starting it next month. He says a nurse shall visit me at home to go through everything - which is odd, being a tablet.

I'm a bit concerned, as I when I get stressed , I break out in a shingles rash. And leaflet says one may not be compatible with it.

[bernese1225 in reply to weymouth321]

Hi, sorry for the late reply. I’m really happy with it so far. I was screened for TB before I started and was told to stay away from anyone with infections i.e shingles/chickenpox. I would speak to the nurse tomorrow and see what she says. Keep me posted. I hope it works for you if you try it, good luck 🍀

[weymouth321 in reply to bernese1225]

Thanks Bernese,

Yes, there's a Rheu hospital Helpline open from 3-4 today, so taking your advice and run it pass her. I wanted to ask you, seeing you have been on it for few months. Shall update you later.

[weymouth321 in reply to weymouth321]

Yes, rang and asked Rheu Nurse whether to take Baricitinib when break out in shingles rash when get v. Stressed - She advises it being firstly important to get the inflammation under control - and should be fine.

[linziej]

Hi

After an initial good response it doesn’t seem to be working.

Blood results have shown no reduction in inflammation and my platelet levels are over 900.

Back in 2 weeks to see what happens next.

How are you getting on?

[linziej in reply to linziej]

Sorry didn’t see your message.