I went to get my knee drained of fluid last week and the doctor also gave me a cortisone shot in the knee. That night I also started my first medicine for RA (hydroxychloroquine- was just diagnosed this month). The next morning I was completely symptom free and have been for a week now. I was wondering if this was the result of the shot, which people tell me it takes 3 days to even kick in, or is it my medicine? I read up on the medicine and it says it takes 6 weeks to even start helping with symptoms. My RA factor is only 19. Since this is so low could it possibly be the medicine helping me?