Has anyone experienced hot flushes/night sweats/exces... - NRAS

NRAS

37,276 members46,139 posts

Has anyone experienced hot flushes/night sweats/excessive perspiration from methotrexate? If so, does it wear off or has anyone any tips?

Dayli1 profile image
17 Replies
Written by
Dayli1 profile image
Dayli1
To view profiles and participate in discussions please or .
Read more about...
17 Replies
kizzy12 profile image
kizzy12

hi ..have been on methotrexate for 9 years but the sweating and feeling hot all the time only started about a year ago so not sure if its the meds or just part of the disease...no-one seems to have an answer x

Strangely, MTX gives me the chills for a couple of days.

I think RA used to give me hot flushes, like menopausal syptoms, but not now that the meds are doing their stuff.

avjh profile image
avjh

Hi I have suffered from this and I thought it was the methotrexate but I've since discovered it was a side effect of the painkiller Zydol.It might be worth checking through the side effects of any other medication you are taking .Hope this helps.

rattusrattus profile image
rattusrattus

i personally think it's part of having an inflamatory disease and not the mtx as my sweating and burning up (i dont want to call them hot flushes!) about 2 years before the joint pains started.

Caza profile image
Caza

Morning,I don't take MTX I take hydroxy & the night sweats have almost stopped so reckon it was the RA. I can't take any painkillers so it can't be them. Hope this helps x

Dotty7 profile image
Dotty7

I'm constantly warm, apart from when I'm hot. Like rattusrattus, I think it goes with the disease - it's like having a mild viral infection and being a bit feverish all the time.

Dotty x

Treesha profile image
Treesha

Absolutely have all those things but it started before I was prescribed mtx. My thoughts are that it is RA related. Tricia x

I agree with other people it seems to be part of the RA to have a low-grade fever/ sweats. As the medications affect all of us differently it's quite likely that these are implicated too - I know that taking ibuprofen brings me out in a sweat.

Cece x

Traceymummy profile image
Traceymummy

I understand the night sweats as symptomatic of auto immune diseases

coetzeegisela profile image
coetzeegisela

Greetings-night-sweats 2am-4am each night, no meds but recovering 'serious vestibular injury'.Now age 44. Athletic, fit. GP suggests anxiety-possible but think am beyond that.They are curious interruptions.Am interested in others' experiences similar.

Kittykatxxxxx profile image
Kittykatxxxxx

Hello ive just started methotrexate and I get these flushes aswell grrrr very annoying. But havn't had any this week maybe I won't ?! Hope this effects wears off

Luan profile image
Luan

I suffer with night sweats so bad always have from day one of being diagnosed 5 years ago started MTX about 3 years ago and still get the sweats started humera about 6 months ago and the night sweats have eased so I thing iris just the condition and unfortunately there is no medication for them I have asked everyone! So sorry it's just one of those things we have to bear and it's not nice I have seen me changing my bed and showering 3 times during the night they are awful

Tiredofdrugs profile image
Tiredofdrugs in reply toLuan

Very curious, do you take Methotrexate and Humira for RA? i take them for an autoimmune disease of the eyes caed Birdshot, a form of Uveitis. I sweat a lot but I also take other meds that can cause this too! Very frustrating!

IMHOT62 profile image
IMHOT62

This was interesting. A LOT of people suffered this problem on Metho. ehealthme.com/ds/methotrexa...

CynC profile image
CynC

I have been taking Metho for about 2 years now and still get regular hot flushes day and night. My doctor says it is not from the drug, so what is it from, no one can tell me. Spoke to another doctor and he says it is a possible side effect of the drug. Guess we just have to live with it.

Cynthia

Tiredofdrugs profile image
Tiredofdrugs

It truly sucks doesn't it!?

anneodomini profile image
anneodomini

before developing RA and starting on methotrexate (15mgs /week) 2 months later, I had been free from hot flushes for 2 years, after suffering them for 11 - 12 years from the age of about 56. They started up again a couple of months ago afer having been on methotrexate for about 6 months.

Not what you're looking for?

You may also like...

Moderation team

See all
KateL-NRAS profile image
KateL-NRASAdministrator
Donagh-NRAS profile image
Donagh-NRASAdministrator
Nicola-NRAS profile image
Nicola-NRASAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.