18 mos after my last Ocrevus infusion my B cells are finally coming back. They were zero when checked at 9 and 11 and 13 mos after that last infusion. Now they are 1.7%
My understanding is that they need to be at least 10% to. Mount any minimal response to a vax. Rechecking in 6 weeks because the doc says they snowball back after they reappear.
Then I guess I re-vax 🙀 but glad the B cells have joined the party again 😊
I'm glad for you 
I hope their numbers come back up quickly. Take care of yourself.🤗
Congrats!! 🎉 Ty for sharing! How many doses did you have prior?
5-6
Yes, it IS time for a party! Congratulations! May they multiply quickly.
Yay! Are you switching DMTs? I'm considering Mavenclad, but would need my B cells to regenerate first. Neuro said that it may take 1 year. From your experience, sounds like it will take much longer.
didn't hear about this before ,so i guess i will ask the doctor about it ,i have an appointment on the 17 th of this month.....thank you for the info...have a great day well actually a great future with good info on your MS...love and much happiness...
I’ve read 6-18 mos. Longer return Bs for lower bmi .No dmt because they say I’m ppms so just healthy lifestyle.
Wow. I didn't realize that your Dx had been switched to PPMS. Does your healthy lifestyle include dietary changes?
It definitely did at first…then seemed to make no difference 🤷🏻♀️
That happened to me too. It seemed !Ike the last infusion was just saline.
I mentioned that to my old neuro that some of my O infusions seem like "saline". His eyes grew wide in concern as there was a report here at the local hospital of one of the RNs substituting saline for pain meds. But, I doubt that any drug user would want to steal Ocrevus.
You would be surprised what people would do. They know that drug is expensive & can get a good price on the black market that sells to crooked doctors.
Yikes! We'll never know if these invisible, side effect free drugs work or not.
i wish you many many b cells. May they grow up to be big and strong and give birth to new little b cells of their own.
i got my art supplies yesterday. You?
yep, don't peek in the envelopes 
And without your B cells are you sick more often??
Omg if it’s not one thing it’s another!
Happy for you🙏🏾
Hurrah! I'm glad they are coming back!
Hi! Im just wondering why your doc is checking your B cells. I also was on Ocrevus for 2 years and have been on nothing for the last 2 years . I know the B cells are slow to come back but I don’t understand how that effects the vaccines. I had 2 Pfizer vacs and then monoclonal antibodies when I got covid 6 months later. I just saw my neuro and she’s not concerned with the B cell count yet she does want me to get boosted ASAP.
Because I had NO response to the covid vax’s
I am so happy for you! I went through my 1st half infusion,2nd half infusion and 1st full dose 6 months ago. Very little change did I see. This month or next I’ll get another full dose. Have been feeling doubtful until I saw your comment. Thanks for restoring my faith in the medicine!
Yes, I had stopped. Last infusion was Nov 2020
Congratulations!
Please explain why that’s a good thing because I honestly don’t know. I thought the point of O was to get rid of the B cells - that they weren’t wanted? I’m just finishing 1year of O and I’m done. Maybe going to try Kesimpta next because I felt like O was an overdose for me! (I weigh 100 lbs)
It is the point and I wish Ocrevus was still working for me but I didn’t think it was and weighing the pros and cons, I was more concerned about covid.
Yes…believe it or not the hematologist/ oncologist they referred me to because they didn’t believe my zero B cells at > 1yr were due to Ocrevus, nor the neurologist I’m seeing were aware of Evusheld. Neuro is referring me to infectious disease doc to discuss Evusheld. Grrrr 😖
when i asked my insurance about evusheld they said they never heard of it.
glad for you. if you don't need Ocrevus every 6 monts than take it as a blessings. every 8 months or so work for me. always have blood tests to check. if your B-cells are not back up, you don't need it!
My neuros say they don’t routinely check B cells 😵💫
so i'm in the not understanding camp. we want the B cells to come back but don't they attack the myelin? And i hope you are doing well overall. No matter what your B cells are doing.
You’re correct. B cells bad…unless you want them in order to develop antibodies to vaccines. We need DMTs that specifically target the MS myelin attacking B cells. Drugs being developed 🤞
That's what I understand, erash I was part of a study that measured my b-cells and my antibodies that I had after 2 shots. Not only did I have no antibodies ~ zero ~ but I have no evidence of ever being exposed to COVID! I have my doubts of the booster helping me. Until I am convinced of that, I am hesitant of getting it because I will be vaccinated but not protected ~ again.
that's why I got the Evusheld shots
i am cautiously optimistic of Evusheld, erash 
Glass half full… I just received my second round since the FDA has adjusted its dosing🤪
I am still full steam ahead with Ocrevus, erash
Wishing you success with O. You might want Evusheld then…what does your Neuro say?
I just started seeing a new neurologist here in Arizona. I will ask about Evusheld at my next appointment.
Today I received 2 shots of the evusheld 👍🏽
Blood Test & Ocrevus B-cell repopulation & Covid immunity 
