I have had MS almost 25 years. I have been on all the shots over the years and am currently not on any DMD. Pretty good until about 7-8 years ago, after two flare-ups have a-lot of difficulty walking very far or standing too long! I use a walker when I do need to go out, which took some time to get used to. But it helps me quite a bit. I have a husband and daughter that are very understanding and supportive, but I wish I didn't have to ask for so much help. Trying to stay positive, but it can be challenging!