Am I looking too hard?

[Entwicklung]

Hi all,

New to this part of the forum... I've recently met some wonderful helpful people on some of the other forums here at health unlocked though and very glad I found you all.

I'm chasing some major issues I'm having (all in my bio), and I'm narrowing it down all the time, but on review of my blood results I've recently learned of PV.

I've attached a picture of some results from a recent FBC... (Will also drop additional images in replies as I can't seem to add multiple images at once). Do these look like anything I / the GP should be investigating further in regards to PV?

[Entwicklung]

Haemaglobin 170

Blood test results: haemoglobin estimation 170

[Entwicklung]

White cell count 9.4 , platelets 282

White cell count 9.4

[Entwicklung]

RBC increasing over time

RBC increasing over time

[Entwicklung]

Haemocrit increasing over time

Haemocrit increasing over time

[Entwicklung]

RBC increasing over time

RBC increasing over time

[hunter5582]

I have been there before where you know something is wrong but there do not seem to be any clear answers. It takes a methodical process of tracking issues and ruling out causes until an answer is found. Patience and persistence are essential.

There is nothing in these numbers that scream PV. Some of the symptoms you list in your bio are consistent with PV but are also consistent with a number of other things. Note that anything that induces hypoxia will increase production of RBCs. You could request a MPN Myeloid panel that would test for the three driver mutations, but it seems likely that the results would be negative. If it would relieve your mind to rule it out, it may be worth pursuing.

Wishing you success in finding answers.

[Entwicklung in reply to hunter5582]

Thanks friend, appreciate the advice and honesty.

Something is definitely wrong but as you say l, exactly what it is seems to be quite a puzzle.

I'm working on ruling things out at the moment with some logic behind each decision, but probably driven a bit too much by desperation to be considered methodical.

Again, very much appreciated the honesty, particularly towards the PV. Would the Haemocrit, haemoglobin and white cell counts need to be significantly higher to even suspect PV? In terms of hypoxia, I feel I'm generally a bit low on the O2 saturation compared to others (maybe around 96%), but well within 'acceptable range' as such.