Joint pains

[TB66]

Hi all I was wondering if anyone else withET Jak2 suffers with joint pains… My hands are very sensitive as are my feet but recently I’ve had problems with my elbows , especially when I first get up . I’m starting my chemo tablets tomorrow and I was also wondering what other people have to say about being on these ? Do they help ? Any feedback would be appreciated 😊

[April-May]

Lots of people experience terrible joint pains - as I did in the early days - but after taking Hydroxycarbamide they all went away. Hope you find the same happens when you take yours.

[TB66 in reply to April-May]

Thank you and fingers crossed 🤞 it reduces the pain 😊

[hunter5582]

Joint pain is a known symptom of MPNs. The mechanism of action may be related to bone marrow activity and/or overproduction of inflammatory cytokines. I also experience this issue, with diagnosed osteoarthritis, tendonitis, and plantar fascitis. Inflammation is the key theme in all of these conditions, including the PV. Hydroxy did not work for me and the interferons help with hematologic control but not joint pain. What does work for me for joint pain is curcumin. Under the direction of an Integrative Medicine doctor, I am also taking L-Glutathione and a Pro-resolving Mediator. Specifically targeting systemic inflammation is this way has been very effective. It makes a significant difference in reducing the level of pain and increasing level of function.

Wishing you all the best and success moving forward.

[TB66 in reply to hunter5582]

Thank you I have suffered with bilateral trochanteric pain syndrome for the past 20 years and had two operations . The severity of the pain in awful and I have also had tennis elbow on and off for a few years . So it looks like this could be the reason .. I will ask the GP about the medication you have mentioned.. again thank you

[hunter5582 in reply to TB66]

Curcumin is an herbal supplement. It is the active ingredient in turmeric. Your GP may or may not be familiar with it. My GP is not knowledgeable about complementary health interventions which is why he referred me to an Integrative medicine doctor. It is important to know that cyrumin is not readily absorbed by the body. It is important to find a bioavailable formulation. A medical provider with complementary health expertise can give the best guidance.

[TB66 in reply to hunter5582]

Thank you ☺️

[william-Indo in reply to hunter5582]

Add some black pepper into tumeric will increasing the absorption of curcumin 20 times.Cheers

[hunter5582 in reply to william-Indo]

Piperine is one of the approaches to making curumin more available. Liposomal formulation is another. regardless of the approach, it is worthless if it is not bioavailable,

[micky10]

Hi, I was diagnosed in April, ET & JAK2 was having joint pain, mainly wrist & elbow. Since taking aspirin everyday the pains have stopped.

[TB66 in reply to micky10]

Thank you 😊

[Planting]

hi

Yes I have experience of hydroxy and have been fine on it. I do have joint problems and hydroxy hasn’t been a cure for them but it keeps my platelets behavin the problem for me now is that I have to embark on a chemo radiation path for 5 weeks and have to give up the hydroxy for 8 weeks. Only been off it 2 days and my feet are really sore. Whether this because of giving up the hydroxy for the moment after 8 years I don’t know. I’ll keep you posted. Good luck to you bit scary at first but I’ve been fine on it

[TB66 in reply to Planting]

Good luck and thank you 😊