Curcumin Real Clinical Study, Anti Inflam - MPN Voice

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Curcumin Real Clinical Study, Anti Inflam

EPguy profile image
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Came across this one. I think it's a rare Curc study using real people, vs animal or lab tests. It's looking for benefits in kidney disease. I was looking to find whether Curc might be a negative for kidney but positive implications come up for reasonable doses.

clinicaltrials.gov/ct2/show...

One goal was below. These inflammation factors show up often in MPN discussions, so could be relevant to us.

<<Get blood samples to evaluate the supplementation effects in inflammatory biomarkers- factor nuclear kappa B (NFkB), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha)>>

They were using 1500mg/day plus piperine which makes Curc more available. The pills many of us are taking have this or other additions to get this added effect.

There are results here:

pubmed.ncbi.nlm.nih.gov/322...

<<a significant decrease in NF-kB mRNA expression (AU) [from 1.08 ... to 0.52>>

So a bad factor relevant to MPN was cut by half.

<<...suggesting that oral supplementation of curcumin may have an anti-inflammatory effect in this patient group. >>

Only n =14 received the therapy, 14 got placebo. All were dialyses patients.

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EPguy
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Mostew profile image
Mostew

Thanks for link .. Always good to see research on actual people . I'm sure we react differently to animals ...

Not enough goes into researching natural remedies....

Bluetop profile image
Bluetop

Thanks for posting. Good to see testing on humans.

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