Fragile X

[Sevenpurple]

My daughter was told my her doctor today that she is in the grey area for fragile X. Does that mean her offspring could possibly have it?

[Hidden]

Hello 👋🏻. I am no expert but recently I have been researching Fragile X as I suspect my son is affected. I came across this info which might help you?

fragilexcarrier.com/patient...

Fragile X intermediate or grey zone carriers

Fragile X intermediate carriers or grey zone carriers have an even smaller change in the fragile X gene and occurs in ~2-3% of the population. They do not have symptoms of fragile X nor are they clearly at risk for the health issues sometimes seen in premutation fragile X carriers.

Male and female intermediate fragile X carriers have the potential to pass a larger-sized fragile X premutation (but not a full fragile X mutation) to each child. If the larger mutation is in the premutation range, it could lead to health issues in adulthood and risk for a full fragile X mutation in future generations. Because of this, one of the main questions that intermediate fragile X carriers have is: What is the chance of passing a larger fragile X gene change to my children?

For more information on available testing to understand your personalized chance of passing a premutation gene to your offspring, please contact your healthcare provider or genetic counselor for the Xpansion Interpreter® test.

Best wishes and good luck

TTT x

[Sarah_Mencap]

I love TTT's post - I wondered if you had looked on here too - fragilex.org.uk/

Cheers

Sarah

[Sarah_Mencap]

Hi again - I have just seen this blog and I thought you might be interested

sarahbobbeal.blogspot.com/2...

Thanks

Sarah