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Antiphospholipid Syndrome: Hughes' Syndrome

Authored by Dr Colin Tidy, Reviewed by Dr Adrian Bonsall on 05 Mar 2018 | Certified by The Information Standard

Antiphospholipid syndrome is sometimes called Hughes' syndrome. It is a disease that affects the blood and makes it more likely to clot than normal - a thrombophilia.


What is antiphospholipid syndrome?

What is a thrombosis?

What causes antiphospholipid syndrome?

What are the typical problems in antiphospholipid syndrome?

Types of antiphospholipid syndrome

Who develops antiphospholipid syndrome?

How is antiphospholipid syndrome diagnosed?

Who should be tested for antiphospholipid syndrome?

What is the treatment for antiphospholipid syndrome?

What is the outlook for antiphospholipid syndrome?

What else can I do?

Types of antiphospholipid syndrome

APS is divided into two types - primary and secondary:

Primary APS. More than half of people with APS have primary APS. This is APS on its own, and not associated with any other disease.

Secondary APS. This is APS that is associated with another disease, such as a rheumatic disease that affects either the bones, joints or soft tissues. An example is systemic lupus erythematosus (SLE, or lupus). SLE seems to be the disease most commonly associated with APS. Many of the rheumatic diseases (including SLE) that are associated with APS are autoimmune diseases. This means that the immune system (which normally protects the body from infections) mistakenly attacks itself. This can cause symptoms and may damage the affected parts of the body.

Sources for the complete article:

and syndrome%C2%A0hughes-syndrome/

3 Replies

This information is disappointing. Its not accurate when advising on treatment with anticoagulation which is worrying and shows that the authors have not kept up with current studies. Its authored by a GP and reviewed by a Australian paediatrician which sadly are not specialists in the disease. I wonder why the "experts" were not asked to be involved.

Whilst its good that more information is becoming available, its so important that its correct. Patients have a hard enough time as it is without having to second guess what they read and it will just fall into the hands of those that like to mock those of us that are forced to find information on line and then repeat it to only look foolish.

1 like

Thank you for your review! Very important to know!


I have quoted you (anonymously ie a reader from HU) on the LuPUS Message Board!

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