Afatanib side affects

My husband aged 69 was diagnosed with stage 4 lung cancer in January. He has been taking Afatanib for 2 months but the side affects of diorhea and peeling skin on his hands have been terrible. He is taking 40mg and wants to continue despite the side affects but the oncologist says that he could be lowered to 30mg and she has had good results. Anyone else having side affects with this medication x

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4 Replies

  • Hi Carole

    Welcome to the forum and sorry to hear about your Husbands side effects, which are known of this medication.

    As the Oncologist has advised 30mg, it may give him some relief on the severity of the side effects. I was unsure from your blog if the Oncologist knows that he is not reducing his dose, if not perhaps let the Oncologist know if he has decided to stay on 40mg , or his lung cancer specialist nurse , especially if you think the symptoms have worsened.

    Skin care is as you probably know, is keeping it hydrated, preventing dryness and protection from sunlight, friction and injury. I have placed a link below for skin and nail care whist having treatment:

    The following link gives some advice on managing diarrhoea from cancer research uk

    If you wish to discuss anything you can call us on our free nurse led helpline number on

    0800 358 7200

    All the best

    The Roy Castle Support Team

  • Thank you for the links I will have a look at those. When we last saw the oncologist she suggested if he couldn't cope with the side affects she could reduce it down to 30mg. He wants to keep on 40mg until he has his first scan to see if it has had an affect we are due to see her on 24th April

  • Try body shop hemp handcream. I take a similar drug and the skin tound my nails are splitting and getting infected. Its much better since I started using the handcream

  • Thank you I will get it for him to try x

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